Dr Efevretis
Rigorous analysis of biomedical research. Science deserves scrutiny. BioSkepsis examines the evidence behind scientific claims — so you don't have to take them on faith.
| Platform |  | Pricing | Only free issues | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 37 | Founded | 4 months ago | Last Issue | 3 days ago |
| Active | |||||
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drefevretis.substack.comLatest Issues
AI for Competitive Intelligence in Pharma R&D
Pharma R&D teams tracking oral therapeutic pipelines face a compound problem: the primary literature grows faster than any analyst can read, general-purpose AI tools hallucinate up to 20% of citations, and unverified synthesis creates direc...
In vivo CRISPR-Cas9 editing of hepatic KLKB1: LNP-mediated delivery, contact pathway silencing, and permanent kallikrein reduction in hereditary angioedema
Hereditary angioedema (HAE) is driven by unregulated plasma kallikrein activity that generates excess bradykinin, causing recurrent episodes of life-threatening tissue swelling. NTLA-2002, an in vivo CRISPR-Cas9 therapy delivered systemical...
cfDNA Multi-Cancer Blood Tests: Methylation, Fragmentomics, and Protein Biomarkers for Early Tumor Detection
Multi-cancer early detection (MCED) blood tests combine cfDNA methylation profiling, fragment-length analysis, and circulating protein biomarkers to screen for dozens of malignancies from a single blood draw. This methods review examines ho...
Can Dual GLP-1/GIP Agonism Stabilize Upper Airway Patency and Coronary Perfusion Through eNOS Signaling?
GLP-1 receptor agonists now reduce MACE, improve heart failure outcomes, and treat obesity-associated obstructive sleep apnea. But the question remains: are these benefits driven by weight loss alone, or does dual GIP/GLP-1 receptor activat...
AI for invasive species risk assessment
During this article we will analyze an example of a research study
Predator Reintroductions Can Destabilize Ecosystems Under Climate Stress: Trophic Cascades, Mesopredator Release, and Pathogen Dynamics
Reintroducing apex preda...
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Rigorous analysis of biomedical research. Science deserves scrutiny. BioSkepsis examines the evidence behind scientific claims to not take them on pure faith.
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