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Latest Issues

No, the Ebola Virus in DRC Probably Isn't "Mutating" — Here's What the Genomes Actually Show

I got this Guardian article in three separate group chats within an hour of it posting:

“Ebola virus behind massive outbreak in DRC could be mutating, officials say.” (1)

Thanks for reading Larry's Substack! Subscribe for free to receive...

3 days ago
1

When AI Biosafety Safeguards Block Public Health

I have spent over three decades of my career working on pandemic preparedness, biodefense, biosafety and biosecurity. I understand why advanced AI systems need safeguards against biological misuse.

What I did not expect was to have those s...

7 days ago
2

A Bundibugyo Vaccine Milestone—and an Access Commitment Worth Noticing

Some milestones deserve to be marked.

Moderna has vaccinated the first participants in a Phase 1 clinical trial of mRNA-1469, its investigational vaccine against Bundibugyo ebolavirus. There is currently no approved vaccine against this sp...

7 days ago
1

Day 75: How Bundibugyo Science Reached the Clinic

Seventy-five days into the Bundibugyo virus (BDBV) outbreak and the situation remains difficult. As of July 30, the Democratic Republic of the Congo (DRC) had reported 3,605 confirmed cases and 1,587 deaths, a crude case fatality ratio of 4...

10 days ago
5

Beyond the First Sequence: Why Pathogen Access and Benefit Sharing Must Reflect How Countermeasures Are Actually Developed

Track contribution, not ownership. That should be a starting principle as World Health Organization Member States continue negotiating the Pathogen Access and Benefit Sharing (PABS) Annex to the Pandemic Agreement. Provenance matters: count...

13 days ago
2

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  • Larry Kerr

    Larry Kerr, PhD is DVP of Global Health & Multilateral Affairs, PhRMA. The opinions expressed here are his own and do not represent those of his employer. @Lawrence Kerr

  • Summer Galloway

    Writes on pandemic preparedness, biodefense, health security, and national security, focusing on governance, strategy, and architectures under real-world pressure. Molecular virologist by training with experience at DoD, CDC, HHS, and Emory.

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