Nano Thoughts
Ashwin GopinathThoughts about rapidly growing convergence between biology, data science thanks to several semiconductor technologies and robotics. Written by AG, and friends, in between arguing about immortality and lemon picking.
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 53 | Founded | 6 years ago | Last Issue | 4 days ago |
| Active | |||||
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nanothoughts.substack.comLatest Issues
Making People More Productive Doesn’t Make the Company More Productive.
TL;DR
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Increasing individual productivity doesn’t increase company productivity, because of friction at the handoffs is a bigger issue than individual productity.
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Make one of ten people 100× more productive and the task finishes...
The Instinct Thesis: Why Memory Is Becoming the Moat
TL;DR: My hypothesis is that Instinct feels magical not because of an inimitable agentic engine, but because of its memory architecture. Just as ChatGPT marked the era of foundation models and Devin/Claude Code marked the era of autonomous...
The Church of Recursive Self-Improvement
On the surface, Silicon Valley’s AI boom looks like a classic venture capital money fever. This is not unlike what we have seen before with them chasing made-up internet currencies or valuing a luxury juice-squeezing machine at half a billi...
Rent the Intelligence. Own the Context.
In a recent X post, Chamath warned consulting firms that deploying Anthropic or OpenAI directly into their organizations is “letting the fox into the hen house.” That warning feels sharper after OpenAI launched the OpenAI Deployment Company...
Cheap Intelligence Makes Accountability Expensive
The strange thing about better AI is that it may not reduce the need for human judgment. It may multiply it.
Once agents are useful, companies will not use them sparingly. They will use them everywhere: to draft customer emails, update tic...
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The writers behind this newsletter.
Experimentalist/founder/Prof splitting time between Boston, SF and SD with "strong" opinions about everything under the sun.
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