The Dependent Variable
Rebuilding cardiovascular physiology from first principles.
| Platform |  | Pricing | Freemium | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 23 | Founded | 5 months ago | Last Issue | 8 days ago |
| Active | |||||
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thedependentvariable.comLatest Issues
ScvO₂: Complicated Ways to Learn Very Little, Part 1
Modern haemodynamics has produced an impressive collection of numbers. Some are measured, some calculated, some are ratios of other calculated numbers, and some require enough algebra that they acquire an air of authority before anyone has...
From Pressure–Volume State to Venous Return
Part 2: How blood distribution and vascular accommodation shape flow
Part 1 stayed deliberately with the static circulation. We started with a simple elastic container and built up the ideas of V₀, stressed volume, compliance, capacitance...
The Pressure–Volume State
Physiology papers often use terms such as stressed volume, unstressed volume, compliance, capacitance, vascular tone and mean systemic filling pressure within a few paragraphs of each other. They are closely related, but they describe diffe...
Acid–base, Part 3: A question of interpretation
Someone hands you a blood gas. The standard base excess is −8.
What caused it?
Part 1 took us through H⁺, buffers and the first reading of a blood gas. Part 2 went deeper into the chemistry and explored how the composition of plasma chang...
Acid–base, Part 2: A question of independence
Stewart, bicarbonate and who’s actually in charge.
In Part 1, we followed molecules picking up and releasing H⁺. We saw how those exchanges settle at a balance, how the tiny amount of H⁺ left free gives us the pH, and how Henderson–Hasselb...
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Rebuilding cardiovascular physiology from first principles.
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