
Rebuilding cardiovascular physiology from first principles.
| Platform | Pricing | Only free issues | Publishes | Twice weekly | |
|---|---|---|---|---|---|
| Issues | 11 | Founded | 2 months ago | Last Issue | 5 days ago |
| Active | |||||

It is a period of hydraulic confusion. The venous reservoir appears to supply the force returning blood to the heart, while the cardiac pump merely restores what has been lost. But an old law of physics has been disturbed. A reservoir that...
It is a time of uneasy equilibrium. The phantom pressure has been challenged, but not defeated. A fixed volume of blood still stretches compliant vessels, storing energy and limiting the circulation’s possible states. Now a new defender has...
The gradient has survived the rebellion. Mean systemic pressure still appears to sit upstream of the right atrium, driving blood home. But as George Brengelmann opens the black box, a troubling question emerges: where, in the flowing circul...
It is a period of haemodynamic uncertainty. The gradient has been challenged, the numerator has struck back, and the old equation can no longer explain itself. From the compliant depths of the venous circulation, a forgotten state is about...
A new gradient had entered the circulation…
In 1955, Arthur Guyton changed the way physiologists thought about cardiovascular function. The circulation was no longer viewed simply as a heart pumping into a passive network of vessels, but a...
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Rebuilding cardiovascular physiology from first principles.
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