Big Pharma Sharma
Unvarnished takes on Big Pharma strategy, M&A patterns, and competitive positioning. What CEOs are actually signaling—before Wall Street sees it
| Platform |  | Pricing | Freemium | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 109 | Founded | 3 years ago | Last Issue | 10 days ago |
| Active | |||||
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bigpharmasharma.comLatest Issues
Last Week Tonight in BioPharma: Week of May 11th, 2026
Welcome back to Last Week Tonight in BioPharma (LWTB). What a week!
This week, BMS wrote a $600M check to Hengrui as part of a staggering $15.2B China licensing deal. Novo dropped new obesity data showing high-dose WEGOVY hitting 28% weigh...
We Know JAK About Myelofibrosis
Myelofibrosis treatment hasn't changed much for a long time. Is there a breakthrough on the horizon?
Of all the types of cancers, blood cancers have perhaps seen the most meaningful therapeutic advances. People often joke that blood cancer...
Last Week Tonight in BioPharma: Week of May 4th
Welcome back to Last Week Tonight in BioPharma (LWTB). What a week!
This week, Cytokinetics hit it big non-obstructive hypertrophic cardiomyopathy setting up strategic crossroads, FDA instability crops up once again with Marty Makary like...
Last Week Tonight in Biopharma: Week of April 27th, 2026
Welcome back to Last Week Tonight in BioPharma (LWTB). What a week! I had a hard time pairing this one down given all the interesting activity we saw. Many deals, data readouts, and strategic updates left on the cutting room floor.
This we...
Should You Be Allowed to Bet on Whether a Cancer Drug Works?
My initial view on prediction markets for clinical trials
Earlier this month a new prediction market got a lot of attention on X. It’s called Endpoint Arena. Similar to other prediction markets, like Kalshi and Polymarket, it allows users...
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Authors
The writers behind this newsletter.
Drug Strategist. Delivering insider analyses and insights on all things BioPharma.
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