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Genes, Minds, Machines

Claus Wilke

Genes, Minds, Machines: Thoughts about Science, Communication, and AI. A newsletter covering topics in biology, data visualization, effective communication, AI, and higher education.

Platform
Substack
PricingOnly free issuesPublishesTwice weekly
Issues51Foundeda year agoLast Issue7 days ago
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blog.genesmindsmachines.com
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Latest Issues

It still wasn’t a lab leak

Early in the COVID pandemic there was understandable confusion over the origin of the virus causing it. The virus, SARS-CoV-2, was similar to the earlier SARS-CoV-1, which had led to illness and death in 2002–2004, but it was also sufficien...

7 days ago
35

Anthropic has not solved the peptide-binder design problem, but maybe bi[o]hub has

In my recent post about Claude’s protein design efforts, I said that I was looking for a 2–3 sentence explanation of how Claude consistently did better than the collective field of human protein engineers, when it was using the same tools t...

19 days ago
15
5

Has Anthropic solved the peptide-binder design problem?

You know what they say about headlines that are yes/no questions. If the author felt confident the answer was yes he would have said so.1 With that out of the way, let’s talk about the recent claim by Anthropic and see what we can find out....

21 days ago
35
3

I'm sorry, you're not going to die from an AI-engineered supervirus

Opinion writer and economist Noah Smith just dropped an article about AI-designed superviruses. Oh man. I used to think Smith was a person with informed opinions, but reading his take on a topic close to my own expertise makes me question t...

23 days ago
145
61

Protein language models are overly constrained by covariation

By many measures, protein language models (pLMs) perform exceptionally well at various tasks in protein research. They are great for homology search, functional classification, and even contact prediction. They can also be useful in evaluat...

a month ago
20
6

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    Science, Communication, AI

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