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Genes, Minds, Machines

Claus Wilke

Genes, Minds, Machines: Thoughts about Science, Communication, and AI. A newsletter covering topics in biology, data visualization, effective communication, AI, and higher education.

Platform
Substack
PricingOnly free issuesPublishesTwice weekly
Issues46Foundeda year agoLast Issue9 days ago
Active

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blog.genesmindsmachines.com
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Latest Issues

The error bar cargo cult

If you’re an experimental scientist and you dare to visualize your results without showing error bars you’ll immediately get challenged. “Can you show some error bars please?” “Did you do any replicates?” “Is the result significant?” But ad...

9 days ago
32
6

Nene Royal—A generational talent

The people of the internet are losing their mind over a 16 year-old girl from Thailand, Nene Royal, whose audition for America’s Got Talent was aired on July 7, 2026. If I told you a meek young girl from Thailand wowed the audience by singi...

12 days ago
11
3

If the work is good why does it need a story?

I recently wrote about how to present research or other technical work by telling a story. This is a topic dear to my heart. I teach this material in my undergraduate and graduate classes, and I have given countless presentations on the top...

21 days ago
26
9

How useful are zero-shot predictions of mutational effects?

When you read papers about AI models for zero-shot fitness predictions,1 you generally get the sense that these predictions work quite well. Correlations between measured fitness effects and zero-shot predictions tend to be high. Systematic...

a month ago
15
3

“Tell a story” is not helpful advice

A common piece of advice we hear about giving presentations or writing scientific reports is “tell a story.” I’m fully on board with this advice. Yes, absolutely, tell a story. But, what if that’s where the advice ends? What if you don’t kn...

a month ago
28
4

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    Science, Communication, AI

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