Harnessing the forces of Creative Destruction. How business, finance, and technology industries drive prosperity and improve the human condition.
| Platform |  | Pricing | Freemium | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 186 | Founded | 6 years ago | Last Issue | 18 days ago |
| Active | |||||
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creativedestruction.substack.comLatest Issues
Two Years in Six Weeks
On September 2, New York City announced a one-year moratorium on student-facing generative AI for students from the youngest pre-K class through eighth grade, about 600,000 in all. The same day, Los Angeles Unified disclosed that it had alr...
Twelve Meters - Chapter Two: Not Yet
This is a work of fiction.
Real institutions, agencies, locations and a small number of public figures appear as settings and reference points. Everything else is invented: the two agents, the technician, the officers on both sides, the tr...
Twelve Meters - Chapter One: By Procedure
This is a work of fiction.
Real institutions, agencies, locations and a small number of public figures appear as settings and reference points. Everything else is invented: the two agents, the technician, the officers on both sides, the tr...
Prevention Is the Only Real Price Control in Healthcare
The conventional claim that U.S. healthcare spending is a dramatic outlier, and therefore proof that single-payer is required, is overstated.
Higher healthcare consumption in the US underwrites the creative destruction that improves per-i...
Where the Blood Goes
Two drugs earned $71 billion in 2025. Semaglutide and tirzepatide. More than double OpenAI and Anthropic combined. Tirzepatide is now the best-selling pharmaceutical on earth, and both did it, reaching under 2% of the people who qualify.
I...
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Authors
The writers behind this newsletter.
Helping cut healthcare costs from poor nutrition. Sharing insights to drive innovation in Ag, Food, and Health. MD at iSelect, backing 70+ "Food is Health" firms. Ex-Boeing Phantom Works, IoT pioneer (Gridlogix), MIT Sloan, F/A-18 E/F engineer.
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