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Latest Issues

Where should you build in AI today? AI Biostats etc.

With AI becoming capable of not only replicating jobs but also entire companies, the main question is where to build in today's AI world to ride the wave but also be safe from the AI replacing businesses. Listed to the full discussion with...

24 days ago
1

Memory in AI systems? The complicated version!

There are at least 33 distinct types of memory in AI systems (likely tens more) . Most people know about two or three of them, the memorized text session chats, the context window (the text a model can see in one pass) and RAG. Technically...

2 months ago
1
2

The Age of Demos in AI Is Over. The Age of AI Delivery Is Next

By Gene Garrard Olinger Jr. and Darko Medin

For the last few years, AI has lived in the land of dazzling demos. You’ve seen them—an assistant that writes production code in seconds, a model that summarizes 300-page PDFs, an agent that “pla...

3 months ago
2

Vibe / AI coding often fails with Spec driven development. Here is how to succeed!

When using AI coding apps, most people write specs as if the model has:

Thanks for reading Darko’s Substack! Subscribe for free to receive new posts and support my work.

  • perfect memory

  • full project awareness

  • zero ambiguity...

3 months ago

How to use p values CORRECTLY in Statistical analysis and interpretation!

In this video i discuss how to use the p values correctly and avoid mistakes that could ruin the Statistical analysis.

  1. Make sure you understand exactly what the p value is and what it isnt

  2. Multiangle analysis

  3. Internal logi...

4 months ago
2

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Authors

The writers behind this newsletter.

  • Darko Medin

    Writing about AI, data science, and biostatistics: LLM agents, neural nets, causal/statistical thinking, and real applied modeling. Creator of BioAIWorks.

  • Gareth Dyke

    I'm a writer, trainer and academic. I've authored more than 360 academic research papers published in international journals over the last 25 years, including in Nature and Science.

  • Bruno Larvol

    Bruno Larvol, founder of LARVOL, drives AI-powered oncology data, social signal analysis, and expert insights for pharma. He leads a global, remote team with a focus on innovation, transparency, and openly “Building in Public.”

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