GLP-1 and obesity medicine news.
| Platform |  | Pricing | Freemium | Publishes | Daily |
|---|---|---|---|---|---|
| Issues | 418 | Founded | a year ago | Last Issue | 7 days ago |
| Active | |||||
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onthepen.substack.comLatest Issues
Massive GLP-1 Data From ECO 2026
We spent time on the podcast last week walking through what the European Congress on Obesity was likely to bring. The maintenance question was the one we flagged as most important -- not whether these drugs work, but what “staying on them”...
He took Retatrutide 40mg and Proved a Point
Forty milligrams of Retatrutide. That’s the number and the mistake that sets the tone for this week’s episode. A 32-year-old man bought the drug online, started at 10 milligrams, quickly escalated to 20, and then accidentally dosed twice in...
A Molecular Stapler Could Make GLP-1 Drugs Last Longer. Scientists Borrowed It From Bacteria.
The body has always known something drug developers are still learning: shape matters.
Not just the shape of a molecule as it enters a receptor, but the shape it holds after hours in the bloodstream, after the body has done everything it d...
Semaglutide and Alcohol: A New Study in The Lancet is Worthy of Attention
There’s a particular kind of exhaustion that comes with alcohol use disorder. Not just the physical kind, though that’s real too. I’m talking the kind that settles into your bones after years of trying, having minimal success, and trying ag...
BREAKING: Two Stories That Impact Compounded GLP-1
A federal judge just handed Eli Lilly a mixed ruling in its lawsuit against Empower Pharmacy. At almost the same time, the FDA quietly proposed something that could matter even more long term: formally declaring that there is no “clinical n...
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Authors
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On The Pen is the leading GLP-1 news podcast and platform covering obesity medicine, FDA actions, drug shortages, access policy, and the business of NuSH therapies. On The Pen is a top Substack best-seller.
Building a resource for useful, actionable, and grounded in real-life lifestyle upgrades. Guest writer for https://onthepen.substack.com/
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