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Research Translation

David Newman

Translating Medical and Health Research For All

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Latest Issues

Alzheimer's and Amyloid, A Summary

What you see below is not grape soda. It is urine from a human being—Purple Urinary Bag Syndrome, as it’s called, is quite something to behold.

But it is brief, and happens when bacteria interact with the plastic of a urinary bag. Treating...

5 days ago
7

Alzheimer's and Amyloid 5: The Big Mistake

In part 2 of this series I described a trial in which researchers developed a novel vaccine for Alzheimer’s patients, designed to rid the brain of amyloid. The vaccine worked, clearing amyloid—but their dementia progressed, unabated.

This...

11 days ago
11
2

Alzheimer's and Amyloid 4: The Long Mistake

Over the first three parts in this series we followed the rise and fall of the Amyloid Hypothesis.

The plaques failed. The idea of toxic precursors failed. The most influential oligomer paper in the field was ultimately retracted. By any o...

20 days ago
8
2

Alzheimer's and Amyloid 3: The Mistake of the Invisible Friend

Neuroscientists are not famous for being dumb. So when the following timeline unfolded, they should have understood exactly what it meant:

First, autopsy studies in 1991 and 1992 found that amyloid plaques—supposedly the cause of Alzheimer...

a month ago
18
5

Alzheimer’s and Amyloid 2: Mistakes Of Mice and Men

Last week we reviewed two seminal studies from the 1990s, both showing mathematically that amyloid plaques are, at best, an inconsistent bystander in Alzheimer’s Disease. Plainly, they are not the driving cause.

Hardcore believers may have...

a month ago
13

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  • David Newman

    ER doc fallen from grace, proud dad and data diver. As a former writer for the Times, HuffPo, and others, and author of "Hippocrates' Shadow: Secrets From the House of Medicine", my focus is translating health and medical research.

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