De Novo
MetacelsusAll things synthetic.
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 99 | Subscribers | Read | denovo.substack.com |
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Latest Issues
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What makes a good egg?
As we get closer to being able to grow human eggs from stem cells, it’s important to be sure that the eggs are high quality and safe enough to use for reproduction.1
Androgenetic haploid selection
Eggs are expensive, sperm are cheap. It’s a fundamental fact of biology . . . for now.
Bio links, Fall 2025
I’d like to highlight some biological news that recently came out:
Gratitude for life
A few days ago, I got a call at 2:39 a.m.
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Authors
The writers behind this newsletter.
Metacelsus is a recent PhD graduate whose research focuses on growing human eggs from stem cells. He also writes at https://denovo.substack.com/
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