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Artwork for De Novo

De Novo

Metacelsus

All things synthetic.

Platform
Substack
PricingOnly free issuesPublishesWeekly
Issues73SubscribersRead denovo.substack.com

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#157
Substack
/Science(Free)

Latest Issues

Recent posts by this newsletter. Browse the email archive.

When the magic bullet goes astray

Antibiotics are really just poisons that are more poisonous to bacteria than to humans. The idea goes back to Paul Ehrlich, who had the idea of a “magic bullet” that could kill pathogens. The first successful antibiotic was an arsenic compo...

3 months ago
11
0

Synthetic Specificity

Imagine you’re a Marvel supervillain, developing a cool new gene therapy to allow your sharks to shoot laser beams from their eyes. For this to work, you need to make their retinal amacrine cells express the Super-Luciferase enzyme. However...

4 months ago
10
0

Meiosis Project Update #2

After a year of work, my meiosis project has made it to the zygotene stage!

4 months ago
11
0

Will no one rid me of this turbulent pest?

Last year, I wrote about the promise of gene drives to wipe out mosquito species and end malaria.

6 months ago
15
9

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  • Metacelsus
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