De Novo
MetacelsusAll things synthetic.
| Platform |  | Pricing | Freemium | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 102 | Founded | 5 years ago | Last Issue | 2 months ago |
| Active | |||||
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denovo.substack.comLatest Issues
Merrick Biotech and Ovelle Bio Announce Definitive Merger Agreement
In vitro oogenesis. Now with 200% more Michael Bay!
Forward-Looking Statements: This press release contains forward-looking statements, wild speculation, and outright lies.
What happens when you clone mice for 20 years straight?
This story begins in 1997, the same year I was born. An up-and-coming postdoc at the University of Hawaii, Dr. Teruhiko Wakayama, had just succeeded in creating the first cloned mouse, Cumulina. This was just a year after the birth of Dolly...
Three interesting studies of genetic variation
I haven’t had much time for blogging these days, but I wanted to highlight three cool studies that came out recently, studying the genetics of meiosis, Epstein-Barr virus, and lifespan.
Genetics of meiosis fidelity
Common variation in m...
What makes a good egg?
As we get closer to being able to grow human eggs from stem cells, it’s important to be sure that the eggs are high quality and safe enough to use for reproduction.1
So, let’s discuss: what does an egg need to have in order to develop into...
Androgenetic haploid selection
Eggs are expensive, sperm are cheap. It’s a fundamental fact of biology . . . for now.
Currently, embryo selection can improve any heritable trait, but the degree of improvement is limited by the number of embryos from which to select. Thi...
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| Subscribers | Engagement | 68 | Monthly Web Visits | ||
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Metacelsus is a recent PhD graduate whose research focuses on growing human eggs from stem cells. He also writes at https://denovo.substack.com/
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