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We write about frontier advances in the life sciences, machine learning, and technology, and how their fusion is reshaping the trajectory of life on Earth.

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Latest Issues

On Training Data for Bio AI Models


Special thank you to Chris Gibson, Nathan Frey, Peyton Greenside, Ron Alfa, and several others for insightful conversations throughout the writing of this article.


Intro

One of the largest trends in AI this year has been...

7 days ago
25
1

Without Form and Void: Learning the Residual of Bioprocess Scale

Act I - The Venetian Arsenal

Every swinging church bell and right-angled buttress beckoned to them with clues about the nature of reality.

Commenced in 1104, the Venetian Arsenal rose to prominence in the Seventeenth Century to become...

2 months ago
8

The Melting Point

Can AI Design Better Architecture and Tune Hyperparameters More Efficiently Than Us?

Every machine learning (ML) model is governed by a set of choices made before training begins including but not limited to learning rates, regularizati...

3 months ago
12

On the Foundations of Machine Reasoning

Introduction

It’s in the name—artificial intelligence (AI). Since the 1956 AI conference at Dartmouth, researchers have sought to install aspects of the human mind—perception, logic, reasoning—into machine systems.

Humans and computers...

6 months ago
9
1

Pretraining: The First Scaling Frontier

Introduction

It’s hard to imagine that ChatGPT is only three years old. Its release marked a defining inflection point for the adoption of artificial intelligence (AI). In its wake, AI has become one of the most debated, romanticized, an...

6 months ago
16
2

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  • Frank Gao
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