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Eat Shit and Prosper

Stephen Skolnick

The greatest unexplored frontier in human health and disease: the gut microbiome

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Substack
PricingOnly free issuesPublishesWeekly
Issues44Founded4 years agoLast Issue3 months ago
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Latest Issues

Now Recruiting: The Cassiopeia Program

We’ve gotten a lot of new subscribers recently—welcome, all of you!

If you’re a new recruit, you may not be aware: I don’t just talk shit, so to speak. Microbiome science is my full-time job. My company, Constellation Bio, is focused on t...

3 months ago
10
2

The Problem With Beta-Carbolines, Part III

Earlier this year, I wrote about the etiology of schizophrenia, positing that psychotic disorders are caused by an overabundance of gut bacteria which produce the psychoactive chemicals tryptamine and phenethylamine.

The genesis of the hyp...

5 months ago
22
7

The Problem with Beta-Carbolines, Part II

There’s a joke among scientists that goes something like:

“A month in the lab is a great way to save yourself an hour in the library.”

It happens all the time: in the course of your usual work, you stumble across some intriguing and unexp...

5 months ago
15
1

The Problem with Beta-Carbolines, Part I

A: …not much, it turns out.
But for a while, it looked like the answer was “beta-carbolines”.

See, the problem with beta-carbolines is that it’s very hard to look for them without accidentally producing some. This means that, if you’re...

5 months ago
12
2

The Statue in the Cave

With apologies to Joey Comeau and Emily Horne.

I swear to god, the next time someone sends me a link to a ChatGPT “analysis” of one of my articles, there’s going to be an unfortunate mixup in my postal logistics-handling spreadsheets, such...

5 months ago
20
7

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  • Stephen Skolnick

    Poop scientist, out to start a movement. A bowel movement, if you will.

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