Policy and Practice
Adam KroetschExploring innovation in health and medicine, and the institutions, incentives, and infrastructure that drive it.
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 16 | Founded | a year ago | Last Issue | 4 months ago |
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Clinical trial innovations don't scale. Here's why, and how to fix it.
Clinical trial innovation has a scaling problem. For years, reformers have pushed innovative ideas to improve trial design and make trials more efficient. Too often, however, these ideas are presented in research papers, demonstrated in pil...
Who Owns the FDA's Thinking?
The FDA is charged with approving drugs only once they are shown to be safe and effective. But what does it mean for a drug to be safe and effective? And, equally importantly: how do the drug makers know whether they’ve provided sufficient...
To fix trials, we need to pay attention to the boring stuff
This post is part of the Clinical Trials Efficiency Project. The purpose of the project is to identify and promote reforms to make trials faster and cheaper. If you have ideas on how to make clinical trials more efficient, please email me....
Introducing the Clinical Trials Efficiency Project
I’m excited to share that I am launching a new research project on systemic reforms to reduce the cost of clinical trials, funded by a grant from Coefficient Giving (formerly Open Philanthropy).
Over the past few months, I’ve been writing...
How The FDA Remade Drug Development
I have a new piece out in Asterisk Magazine: “Reputation (FDA’s Version)”
It’s a review of Daniel Carpenter’s epic 2009 history of FDA pharmaceutical regulation, “Reputation and Power”. I walk through the history of the FDA as told throug...
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Authors
The writers behind this newsletter.
Former FDAer. I write about innovation in health and the policies, institutions, incentives, and infrastructure that make it possible.
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