The Syringe Runneth Over
Gabriel Alizaidy, MD, MSTrial, error, and optimization: Using peptides and hormones to build a better version of myself for my wife and kid.
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 10 | Founded | a year ago | Last Issue | 11 days ago |
| Active | |||||
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galizaidy.substack.comLatest Issues
Peptides like BPC-157, TB-500 and MOTS-c can be compounded (for now).
TL;DR
- On October 27, 2026, HHS posted a policy that opens up access to six peptides through 503A compounding pharmacies: BPC-157, TB-500, Epitalon, Semax, KPV and MOTS-c. HHS says the goal is to “expand and improve patient access.”...
Drink more water on GLP-1s
Recently, 2 deaths were reported from retatrutide. Now, at the time of writing this, retatrutide isn’t FDA approved, nor widely available outside of the research-use-only world. Naturally, the news outlets and holier-than-thou folks on soci...
Women Need Different Growth Hormone Peptide Dosing
GHRH dosing should be individual, but most protocols treat it as universal. Goals, lifestyle habits, and individual patient factors rarely enter the equation. That alone is already a problem. The male-female difference is the larger gap, an...
Supercharge Your Tesamorelin with Melatonin
More Than a Sleep Hormone
Melatonin is a crazy powerful hormone and molecule. It is often relegated to sleep enhancement and is left there, which means most people are sitting on something genuinely remarkable without knowing it. The a...
The MOTS-c Hangover Effect
MOTS-c, which stands for Mitochondrial Open Reading Frame of the 12S rRNA Type-C, is one of the most compelling peptides in performance medicine right now. It drives fat burning, improves how your body handles blood sugar, supports mitochon...
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| Subscribers | Engagement | 74 | Monthly Web Visits | ||
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| Accepts Sponsors | Estimated Cost per Ad | ||||
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Authors
The writers behind this newsletter.
I write about hormones, peptides, and the messy trial-and-error of trying to feel better. Research, notes, and the odd admission that I’m still figuring things out. A small place where the syringe occasionally runneth over.
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