Ground Truths
Eric Topol, Dr. Jen Gunter, Robert Wachter, Tom Frieden, Shana Kelley, Seth Berkley, The Road Best Traveled, Matthew Cobb, Dan Buettner, Kevin J. Tracey, MD, Jonathan KipnisFacts, data and analytics about biomedical matters
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 260 | Subscribers | Read | erictopol.substack.com |
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Latest Issues
Recent posts by this newsletter. Browse the email archive.
A Master Class on Sleep
Yo-El Ju is the Barbara Burton and Reuben Morris Professor of Neurology at Washington University, St. Louis. She got her AB from Harvard and MD from Columbia and actively practices sleep medicine and is a prolific researcher, one of the top...
The Flawed V02 Max Craze
In the past couple of weeks I’ve had 2 patients contact me because they were worried: their V02 max was decreasing. Their data were based on smartwatch imputations, which are notoriously imprecise. But the problem is much bigger than that. ...
Why All Mammograms Should Incorporate A.I.
Follow-up of the largest randomized trial of AI in medicine was reported a week ago. The Mammography Screening with Artificial Intelligence trial (MASAI) randomized trial in Sweden of more than 105,000 women compared the interpretation by t...
Robert Wachter & Eric Topol - Discuss a Giant Leap Book
Get more from Eric Topol in the Substack app
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Authors
The writers behind this newsletter.
physician-scientist, author, editor
OB/GYN, author of The Vagina Bible and The Menopause Manifesto (NYT and Canadian bestsellers), appropriately confident, lasso of truth.
Author, "A Giant Leap," Chair, Dept. of Medicine, UCSF
President and CEO of Resolve to Save Lives. Former CDC Director and New York City health commissioner. Focused on partnering with communities around the world to save lives.
Infectious Disease Epidemiologist
Professor Emeritus (University of Manchester), writes on biology, history of science & French Resistance. Author of a biography of Francis Crick, out in Nov 2025.
Dan Buettner is a National Geographic Explorer, Emmy Award-winning producer, 5 X New York Times bestselling author and Founder of the blue zones.
President/CEO of Northwell Health's Feinstein Institutes. Pioneer of bioelectronic medicine, vagus nerve research. Author of "The Great Nerve." Discoveries helped get the first FDA-approved vagus nerve implant.
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