Ground Truths
Eric Topol, Roxanne Khamsi, Joanna Stern, Don Milton, Sebastian Mallaby, Robert Wachter, Yo-El Ju, Dan Buettner, Kevin J. Tracey, MD, Jonathan Kipnis, Adrian Woolfson, Trisha PasrichaFacts, data and analytics about biomedical matters
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 270 | Founded | 5 years ago | Last Issue | 17 days ago |
| Active | |||||
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erictopol.substack.comLatest Issues
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It has been 15 years since the first unequivocal proof that an immune checkpoint inhibitor (anti-CTLA-4, the T cell receptor shown in blue below; pink represents the antibody) was shown to extend survival in patients with metastatic melanom...
Assessment of the Hantavirus with Prof Donald Milton
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Joanna Stern: An AI Immersion for 365 Days
Joanna Stern was the Wall Street Journal technology journalist for 12 years. She’s an Emmy award winner for her documentary E-Ternal, and recently started her own company New Things, with added advice from ChatGPT!
Over the years at WSJ,...
The Paradox of Medical AI Implementation
In 2012, the era of deep learning AI got legs with the convolutional neural network (AlexNet) that won the ImageNet challenge. Those images were everyday objects, animals, and scenes, unrelated to health and medicine. Over 7 years ago, I wr...
Roxanne Khamsi: We Are All Genetic Mosaics
“You are a slightly different genetic version of yourself today from yesterday, and will be different yet again tomorrow.”—Roxanne Khamsi
“Each neuron really is a beautiful and unique snowflake”—Ed Yong
Roxanne Khamsi is one of the leadin...
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Authors
The writers behind this newsletter.
physician-scientist, author, editor
Roxanne Khamsi is an author and science communicator who has been covering discoveries in genetics and medicine for two decades. Currently, she is a contributing writer for The Atlantic. Her new book is Beyond Inheritance: (Riverhead, 2026).
I'm the founder and chief everything officer at New Things. Subscribe at thenewthings.com. I'm also the author of I AM NOT A ROBOT: MY YEAR USING AI TO DO (ALMOST) EVERYTHING. Buy it here! joannastern.com.
Physician, epidemiologist, aerobiologist focused on prevention of airborne infection transmission. @donmilton.bsky.social
Author, "A Giant Leap," Chair, Dept. of Medicine, UCSF
Dan Buettner is a National Geographic Explorer, Emmy Award-winning producer, 5 X New York Times bestselling author and Founder of the blue zones.
President/CEO of Northwell Health's Feinstein Institutes. Pioneer of bioelectronic medicine, vagus nerve research. Author of "The Great Nerve." Discoveries helped get the first FDA-approved vagus nerve implant.
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