Ground Truths
Eric Topol, Roxanne Khamsi, Joanna Stern, Marios Georgakis, Elisa Port, Don Milton, Bad Influence, Machine Readable, Adrian Woolfson, Gut Checker, Aaron Newman, Helen Pearson, Sarah Urbut, MD PhD, Julia Belk, Nathan ZemkeFacts, data and analytics about biomedical matters
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 283 | Founded | 5 years ago | Last Issue | 7 days ago |
| Active | |||||
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erictopol.substack.comLatest Issues
Marios Georgakis: Why Did Two Major Clinical Trials for Heart Disease Fail?
In recent weeks the results (announced by press release) of 2 major placebo-controlled randomized trials—ZEUS, testing an interleukin-6 (IL-6) blocker vs inflammation, and HORIZON, testing a drug to lower Lp(a), indicated failure to achieve...
The Coronary Artery Inflammation Controversy
Why did a big clinical trial that tested an anti-inflammatory drug fail to reduce heart events?
Why did another pivotal trial of lowering Lp(a) fail to reduce heart events?
In this edition of Ground Truths I’ll offer some explanations an...
Two Landmark Studies Challenge Dogma About our Brain Immune Cells and Aging
This podcast is meant to complement my recent Ground Truths post Why Our Memory Slips After Age 50 which has all the relevant links to the 2 papers, key graphics, and other related publications. If you haven’t had a chance to read that, it...
Deborah Cohen: The Wellness-Industrial Complex
Deb Cohen is an award winning investigative journalist and correspondent who trained as a physician and has worked with the BBC and BMJ. She just published BAD INFLUENCE, a book which takes us deep into the wellness-industrial complex—the c...
Why Our Memory Slips After Age 50
There has been a big shake-up in the understanding for how our brain ages. Until now, the prevailing belief was that our brain tissue shrinks with age, exemplified by the hippocampus, the region tied to memory and learning, as seen via MRI...
Key Facts
Audience Metrics
Subscribers, engagement, traffic and sponsorship for Ground Truths.
| Subscribers | Engagement | 83 | Monthly Web Visits | ||
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| Accepts Sponsors | Estimated Cost per Ad | ||||
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| Ranked Keywords | 8.3k | Monthly Search Traffic | Top Keywords |
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Authors
The writers behind this newsletter.
physician-scientist, author, editor
Roxanne Khamsi is an author and science communicator who has been covering discoveries in genetics and medicine for two decades. Currently, she is a contributing writer for The Atlantic. Her new book is Beyond Inheritance: (Riverhead, 2026).
I'm the founder and chief everything officer at New Things. Subscribe at https://thenewthings.com/subscribe. I'm also the author of I AM NOT A ROBOT: MY YEAR USING AI TO DO (ALMOST) EVERYTHING. Buy it here! https://joannastern.com/
Physician-scientist leading a lab at LMU Munich. Writing about human genetics, drug development, and the future of biotech and medicine.
Chief of breast surgery, Mount Sinai Health System. Author of the forthcoming book, The Breast Advice: All You Need to Know About Health, Screening, and Treatment coming May 19 and available for preorder now. Link below.
Physician, epidemiologist, aerobiologist focused on prevention of airborne infection transmission. @donmilton.bsky.social
Paul A. Volcker Senior Fellow for International Economics at the Council on Foreign Relations. Latest book: The Infinity Machine: Demis Hassabis, DeepMind, and the Quest for Superintelligence. Cohost of The Spillover podcast.
I'm Trisha Pasricha, a physician-scientist at Beth Israel Deaconess Medical Center, an assistant professor of medicine at Harvard Medical School, and the 'Ask a Doctor' columnist for The Washington Post
Associate Professor at Stanford University and CZ Biohub Investigator.
I'm a physician scientist at Massachusetts General Hospital and Instructor at Harvard Medical School. I'm passionate about bayesian statistics, genomics, and taking great care of patients. Views are my own.
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