Hussein N. Yassine
Hussein YassineMy personal Substack
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 21 | Subscribers | Read | yassinelab.org |
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Latest Issues
Recent posts by this newsletter. Browse the email archive.
Use It or Lose It
We’ve heard the message for years: sitting too much is bad for you. It’s been linked to heart disease, diabetes, depression, and yes — dementia. So the advice has generally been to sit less and move more.
The Vascular Side of Alzheimer's: A New Hypothesis for Why the Brain Bleeds
Alzheimer’s disease is not just a disease of plaques in the brain. It is also, and perhaps equally, a disease of blood vessels. In many patients — especially those carrying the high-risk APOE4 gene — amyloid accumulates inside the walls of ...
What the World's Oldest Person Teaches Us About Inflammation and Longevity
In January 2023, a woman living in a care home in Catalonia, Spain, became the oldest verified living person on Earth. She had been born in San Francisco in 1907, moved to Spain as a child, and lived through two world wars, a pandemic, the ...
When Your Brain's Immune System Burns Out: A New Way to Think About Alzheimer's Disease
There is a story we’ve been telling about Alzheimer’s disease for decades. Sticky plaques of amyloid-beta protein accumulate in the brain. Tangles of tau protein strangle neurons from the inside. The brain shrinks, synapses fail, memories d...
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Authors
The writers behind this newsletter.
I am a Professor of Neurology at USC. Interested in APOE ε4, lipid metabolism, and dementia risk.
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