IBD Trial Files
TrialFilesFree bimonthly newsletter that summarizes the most significant, practice-changing IBD randomized controlled trials, straight to your inbox.
| Platform |  | Pricing | Only free issues | Publishes | Monthly |
|---|---|---|---|---|---|
| Issues | 33 | Founded | 3 years ago | Last Issue | 4 months ago |
| Active | |||||
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ibdtrialfiles.substack.comLatest Issues
IBD Trial Files: Upadacitinib for UC and IgG antimicrobial antibody response to predict future risk of Crohn’s disease
Long-term efficacy and safety of upadacitinib in patients with moderately to severely active ulcerative colitis: an interim analysis of the phase 3 U-ACTIVATE long-term extension study
Panaccione R et al. The Lancet Gastroenterology an...
IBD Trial Files: Top-down vs Accelerated Step-up Treatment for Patients with New Crohn's Disease and Efficacy and Safety of Maintenance Ustekinumab for Ulcerative Colitis Through Three Years
A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn’s disease (PROFILE): a multicentre, open-label randomised controlled trial
The PROFILE Trial. The Lan...
IBD Trial Files Throwback: Crohn's disease management after intestinal resection and Infliximab, azathioprine, or combination therapy for Crohn's disease
Crohn’s disease management after intestinal resection: a randomised trial
De Cruz P et al. The Lancet (April 2015)
Bottom Line: This randomized trial, conducted between October 2009 and September 2011, involved 174 patients with Crohn’...
Trial Files Guidelines Edition: Crohn's Disease: American College of Gastroenterology 2025
The Management of Crohn's Disease Guidelines were published in 2025 by the American College of Gastroenterology and span 40 pages. The previous guidelines were published in 2018.
LINK TO GUIDELINES
Top 5 Take Home Points
- Mesalam...
IBD Trial Files: Glepaglutide for Short Bowel Syndrome and Guselkumab for Induction and Maintenance in Crohn's disease (GRAVITI)
Introducing Heme-Onc Trial Files, for all of your hematology-oncology RCT needs. Check out the first issue below and subscribe (for free!).
Heme-Onc Trial Files Issue #1
Glepaglutide, a Long-Acting Glucagon-like Peptide-2 Analog...
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Free biweekly newsletter for trainees and staff on General Internal Medicine at Sinai Health that summarizes the most significant, practice-changing randomized controlled trials, straight to your inbox.
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