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James H. Stein, MD

I’m a preventive cardiologist and professor with over 36 years caring for patients and researching cardiovascular disease. I aim to make health and science clearer and more approachable. *Not* monetized. My views, not medical advice.

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Latest Issues

Variability in Lp(a) Measurements: A Brief Primer

This post is a bit of “inside baseball,” or “inside lipidology,” but so many people are having Lp(a) levels measured, and we are asked about repeat values so often, I thought this primer might be useful to you and your patients.

Lp(a) is a...

3 days ago
21
5

Curious Cholesterol Cases from Clinic, #5: When Triglycerides Don’t Match the Body Habitus

“Curious Cholesterol Cases from Clinic” is a series built around real-world lipid cases, some of which look obvious at first glance but turn out not to be what they seem. They are presented as clinical unknowns for teaching purposes and are...

7 days ago
28
6

There’s No Crying in Cardiology!

“There’s no crying in baseball!” Movie still from https://www.mlb.com/news/tom-hanks-talks-iconic-a-league-of-their-own-line.

In the iconic movie “A League of Their Own,” Manager Jimmy Dugan (played by Tom Hanks) tells a sobbing outfielder...

14 days ago
76
17

The Bias We Call Expertise: How It Shapes Clinical Practice Guidelines

Note: My career mentor and dear friend, Norman Fost, MD, MPH, contributed to this essay and helped refine its arguments.

Financial conflicts of interest receive enormous attention in medicine because they can influence interpretation of ev...

18 days ago
29
8

Why I Oppose Universal Lipoprotein(a) Screening

Note: I wrote this before the Lp(a)HORIZON topline results were reported. I had planned to post this in November for the AHA Scientific Sessions meeting, but thought that moving it up was timely after this week’s news.

Three links in the c...

21 days ago
46
29

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  • James H. Stein, MD

    I’m a preventive cardiologist and professor with over 36 years experience caring for patients and researching cardiovascular disease. I aim to make health and science clearer and more approachable. *Not* monetized. My views only, not medical advice.

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