James H. Stein, MD
I’m a preventive cardiologist and professor with over 35 years caring for patients and researching cardiovascular disease. I aim to make health and science clearer and more approachable. *Not* monetized. My views, not medical advice.
| Platform |  | Pricing | Only free issues | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 66 | Founded | a year ago | Last Issue | 7 days ago |
| Active | |||||
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jamesstein18.substack.comLatest Issues
What I Finally Optimized on My Bike Ride
The Joys and Torments of Solitude, Jean-Jacques Sempé, The New Yorker, August 2, 2010
Like most people, I learned to ride a bike when I was a child, but my relationship to it always was practical: finding friends to play with and getting f...
Why “Cholesterol Is Debunked” Arguments Keep Resurfacing
I am starting this essay with a picture.
MRFIT mortality data, drawn from Table 4 of reference 1.
It comes from the Multiple Risk Factor Intervention Trial (1), a study of more than 350,000 middle-aged men, conducted at a time when women...
Five-Star Camps, No Real Medical Care for Miles
Medical care was not on the menu.
We just returned after two weeks in South Africa, Zimbabwe, and Botswana, from a safari that our group of 16 had planned for well over a year. The camps were extraordinary with expert guides, exciting game...
“It looks really healthy, Jim.”
Sunrise. The Elephant Camp, Victoria Falls, Zimbabwe. April 2026.
Yesterday afternoon, before my cystoscopy, I told the nurse I was scared. She looked at me a little puzzled and asked why. After all, I have had dozens of these procedures....
Oops...
Early this afternoon I accidentally published a future Curious Cholesterol Case while rearranging my posts. I unpublished it as soon as I realized what happened. Unfortunately, some of you already received the email.
If you read it and enj...
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I’m a preventive cardiologist and professor with over 35 years caring for patients and researching cardiovascular disease. I aim to make health and science clearer and more approachable. *Not* monetized. My views, not medical advice.
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