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Joseph Raffaele

Joseph Raffaele

Physician-Scientist in Longevity Medicine | Health Analytics Entrepreneur

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Substack
PricingOnly free issuesPublishesWeekly
Issues7SubscribersRead josephraffaele329336.substack.com

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Latest Issues

Recent posts by this newsletter. Browse the email archive.

Can You “Catch” Alzheimer’s?

For years I’ve encouraged my patients to get the Shingrix two-shot vaccination to protect against Herpes zoster, or shingles, but with no particular enthusiasm. I hadn’t even gotten it myself. I could measure the levels of antibodies that t...

a month ago
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From Mood Stabilizers to Magic Mushrooms: What Three Repurposed Drugs Reveal About Telomere Biology’s Role in Aging

Recently, three intriguing academic papers have made the case that three different drugs may produce longevity-enhancing effects, quite apart from the unrelated conditions they’re now being used to treat. I’ve written posts about two of the...

2 months ago
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Medicine Beneath the Surface: Redefining Aging, Disease and Longevity Medicine

A lot of words and a lot of conference time have been expended on a single question: “Is aging a disease?” Or, to put it in more concrete terms, are doctors specializing in longevity medicine just treating the common “diseases of aging” mor...

2 months ago
1
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Repurposing Zetia: How a heart drug may wind up protecting the brain

A few years ago, I started taking the cholesterol-lowering drug Zetia (ezetimibe). My LDL cholesterol was high and I’d already tried and discontinued the usual first-line statin drug therapy, unhappy with some not uncommon statin side effec...

3 months ago
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