Joseph Raffaele
Joseph RaffaelePhysician-Scientist in Longevity Medicine | Health Analytics Entrepreneur
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 11 | Subscribers | Read | josephraffaele329336.substack.com |
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Latest Issues
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Plasmalogens, Controversy, and Scientific Middle Ground: A Response to Christin Glorioso, MD, PhD
First, I want to thank you for taking the time to examine this topic seriously in your Substack article recently. Your piece raises important concerns, and I agree with much of your framing. Where I differ is primarily in emphasis rather th...
The Glycocalyx: The Invisible Sugar Layer That May Decide How Fast We Age
When most people think about heart disease and aging blood vessels, they imagine clogged arteries, cholesterol plaques, or stiff vessel walls. That picture isn’t wrong—but it is incomplete.
Hormone Replacement Therapy as Geroprotective Medicine
A new paper has entered the longevity medicine conversation with unusual ambition and welcome clarity: Perimenopausal Hormone Replacement Treatments as a Geroprotective Approach – Adapting Clinical Guidance. Its central claim is both bold a...
Glycan Biology and Early Disease Prediction: The Next Chapter
This past October, at the Global Longevity Summit in Geneva, Switzerland, I shared a panel on the topic of “biological clocks” with Gordon Lauc, glycan biology pioneer and the developer of the GlycanAge biological clock. I came back to New ...
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