Cancer Ecology Notes
Cancer Ecology by Ken PientaUnderstanding cancer through the lens of ecology and evolution
| Platform |  | Pricing | Only free issues | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 47 | Founded | 5 months ago | Last Issue | 4 days ago |
| Active | |||||
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A Tumor Grows Far Slower Than Its Cells Can
Photo by Daniele Levis Pelusi on Unsplash
A cane toad front sweeps across Australia at fifty kilometers a year. A prairie-dog town creeps outward at thirty meters. A tumor, measured honestly, grows at a fraction of one percent a day, order...
A cancer’s ability to keep changing may be a vulnerability we can exploit for treatment
Photo by Sangharsh Lohakare on Unsplash
When a cancer becomes resistant, we ask what changed. Which mutation appeared, which pathway became active, which cells survived? A second question is how much capacity the population still ha...
Immunotherapy does not strengthen the immune system. It stops the tumor from switching it off.
Photo by Peter Burdon on Unsplash
In 1982 a woman in Scotland had a melanoma removed from her skin. It was 2.6 millimeters thick. The wider excision found no residual tumor. She was entered in the Scottish Melanoma Group registry, followed...
An exhausted T cell may have a point of no return
Photo by National Institute of Allergy and Infectious Diseases on Unsplash
When a patient’s cancer does not respond to a PD-1 inhibitor, the usual question is what the tumor is doing to resist. A second question gets less attention. What i...
Most of Your Cells Cannot Get Cancer
Photo by camilo jimenez on Unsplash
Here is a fact that sounds wrong but is not. Most of the cells in your body cannot become cancer. Not “rarely do.” Cannot. A mature neuron, a red blood cell, a muscle fiber contracting in your hea...
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Authors
The writers behind this newsletter.
A physician - scientist at Johns Hopkins dedicated to understanding and eradicating cancer by utilizing eco-evolutionary principles.
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