Cancer Ecology Notes
Cancer Ecology by Ken PientaUnderstanding cancer through the lens of ecology and evolution
| Platform |  | Pricing | Only free issues | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 41 | Founded | 5 months ago | Last Issue | 5 days ago |
| Active | |||||
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kenpienta.substack.comLatest Issues
Half a Cup of Tumor Can Kill You
Photo by Patrick Ho on Unsplash
In 2012, researchers asked 1,193 people receiving chemotherapy for metastatic lung or colorectal cancer a simple question: did they understand that the treatment was not at all likely to cure them? Sixty-nin...
An isotope ratio may tell you what happened, not just how much is there
Photo by Arash on Unsplash
Most blood tests in oncology measure how much of something is there. PSA, CA-125, lactate dehydrogenase and circulating tumor DNA are all concentrations. A concentration says how large a signal is. It usually can...
Why Your Oncologist Will Not Say You Are Cured
Photo by National Cancer Institute on Unsplash
Researchers at the Dana-Farber Cancer Institute surveyed their own oncology clinicians about a single word. Of the 117 responses analyzed, 81 percent said they were hesitant to tell a patient...
A resistant cancer cell may be held in check by where it sits
Photo by Marita Kavelashvili on Unsplash
Adaptive therapy is one of the more encouraging ideas to come out of evolutionary oncology. Instead of treating at the maximum tolerated dose until the cancer progresses, it treats, pauses and treat...
Screening Does Not Catch a Random Sample of Cancers
Photo by Arno Moller on Unsplash
Last week’s post explained one reason a screening statistic can improve without saving a single life: lead-time bias, which starts the survival clock earlier without moving the date of death. There is a sec...
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| Subscribers | Engagement | 76 | Monthly Web Visits | ||
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Authors
The writers behind this newsletter.
A physician - scientist at Johns Hopkins dedicated to understanding and eradicating cancer by utilizing eco-evolutionary principles.
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