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Latest Issues

Incorporating Microeukaryotes into Biosecurity

Viruses and bacteria dominate discussions of biological risks from AI, but this focus leaves an important gap: microeukaryotes. Protists and fungi include pathogens that can cause serious disease, devastate crops, and produce harmful toxins...

7 days ago
53

An Agent Benchmark for Therapeutic Oligonucleotide Discovery

We introduce TxBench-Oligonucleotide Discovery, a verifiable benchmark of 113 evaluations that tests whether AI agents, working with no internet access, can recover realistic program decisions from experimental data/context that would be av...

16 days ago
15

Quantifying Frontier Model Performance on Antibody Discovery Tasks

We introduce an Antibody Discovery Benchmark, an experimentally grounded benchmark for testing whether AI agents can make scientific decisions across the stages of therapeutic antibody discovery.

The benchmark contains 100 evaluations span...

23 days ago
13

When It Answers, Fable 5.1 is Strong at Biology Reasoning

We’ve run Fable 5.1, Anthropic’s newest model released today, across our full set of benchmarks, including multi-omics, therapeutics, and biosecurity tasks. From the 10,552 trajectories run, we observe qualitative improvements in model reas...

24 days ago
74

Testing Grok 4.6’s Enhanced Biology Safeguards

Following the initial release of Grok 4.6, LatchBio performed testing of the latest-available version of the model on our full suite of biological-capability tests, including BiosecBench-Refusal. This benchmark tests a model’s ability to re...

24 days ago
78

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Authors

The writers behind this newsletter.

  • LatchBio
  • Ramesh Ramasamy
  • Qian
  • Harmon Bhasin
  • Sean Poust
  • Alfredo Andere

    Co-Founder and CEO @ LatchBio

  • Alex Urrutia
  • Arjun Banerjee
  • Anirudh Narsipur
  • Dianzhuo Wang
  • Evan Seeyave

    above average mango eater

  • Hannah Le
  • Kenny Workman

    Co-Founder + CTO @ LatchBio

  • Joel Simonoff

    AI@LatchBio

  • Martin Jacko
  • Vanessa Smilansky

    I'm a Research Scientist developing biosecurity evaluations to promote safer AI. My background spans pathogen genomics, biosurveillance, and pandemic prevention, with an interest in connecting One Health and biosecurity.

  • Christopher Zou
  • Jackson Brougher
  • Dillon Flood

    Latch bio

  • Social

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