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Intelligence Infrastructure for Biology

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PricingOnly free issuesPublishesWeekly
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Latest Issues

Open Source Classifiers Do Not Stop AI Bioweapon Generation

A few days ago Mistral released Shieldstral, its new safety classifier, without disclosing its performance on major biosecurity related tasks, such as viral engineering. We decided to adapt our biosecurity benchmark, BiosecBench-Refusal, to...

9 days ago
71

How Good is Opus 5 at Biology?

Opus 5 results across our biosecurity, therapeutics, and -omics benchmarks are now live on benchmarks.bio, to generally positive results. I’ll share high level numbers first, and then a deeper dive into model and harness quirks we noticed a...

22 days ago
91
2

Surfacing Benchmark-Maxxing in Kimi-K3

Today we released results for Kimi-K3, an open-source LLM boasting GPT-5.6/Mythos-level coding-benchmark scores, across our short-horizon therapeutics and -omics benchmarks on benchmarks.bio. Across nearly every benchmark, K3 performs prett...

25 days ago
100
1

VariantBench: An Agentic Benchmark for Genetic Variant Discovery and Interpretation

Analysis of data from genome sequencing and related assays is an increasingly important bottleneck in clinical and research settings. AI agents hold promise in automating and scaling such analysis.

We present VariantBench, a verifiable ben...

a month ago
63

Why An Open Source Harness Outperforms Claude Code On Frontier Biology Tasks

At LatchBio, we benchmark AI models on frontier-level biology tasks - benchmarks.bio. We’ve seen a trend where harness changes cause large swings in performance on the same model. For example, on TxBench-PP (a short-horizon benchmark), the...

a month ago
44
4

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Authors

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  • LatchBio
  • Kenny Workman

    Co-Founder + CTO @ LatchBio

  • Alfredo Andere

    Co-Founder and CEO @ LatchBio

  • Hannah Le
  • Harihara Muralidharan

    Bioinformatics Engineer @LatchBio

  • Zhen Yang

    Bioinformatics

  • Anirudh Narsipur
  • Joel Simonoff

    AI@LatchBio

  • Dianzhuo Wang
  • Evan Seeyave

    above average mango eater

  • Harmon Bhasin
  • Arjun Banerjee
  • Christopher Zou
  • Social

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