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Quantifying Frontier Model Performance on Antibody Discovery Tasks

We introduce an Antibody Discovery Benchmark, an experimentally grounded benchmark for testing whether AI agents can make scientific decisions across the stages of therapeutic antibody discovery.

The benchmark contains 100 evaluations span...

5 days ago
12

When It Answers, Fable 5.1 is Strong at Biology Reasoning

We’ve run Fable 5.1, Anthropic’s newest model released today, across our full set of benchmarks, including multi-omics, therapeutics, and biosecurity tasks. From the 10,552 trajectories run, we observe qualitative improvements in model reas...

6 days ago
73

Testing Grok 4.6’s Enhanced Biology Safeguards

Following the initial release of Grok 4.6, LatchBio performed testing of the latest-available version of the model on our full suite of biological-capability tests, including BiosecBench-Refusal. This benchmark tests a model’s ability to re...

7 days ago
78

We Can Detect New Pathogens in Days. Can AI Help Us Understand Them?

We introduce BioSecBench-Function, a verifiable benchmark for testing whether AI agents can infer the functional properties of viruses, bacteria, and toxins from data.

The benchmark contains 111 evaluations across five biological threat ax...

11 days ago
16

Grok 4.6 is a Frontier Biology Model

Following yesterday's Grok 4.6 release, we ran it against our short-horizon biology tasks on benchmarks.bio. Across 1716 trajectories we generated, we find that Grok 4.6 sits roughly at Opus 5/GPT-Sol-5.6 level of intelligence while being f...

25 days ago
59

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Authors

The writers behind this newsletter.

  • LatchBio
  • Kenny Workman

    Co-Founder + CTO @ LatchBio

  • Alfredo Andere

    Co-Founder and CEO @ LatchBio

  • Hannah Le
  • Harihara Muralidharan

    Bioinformatics Engineer @LatchBio

  • Zhen Yang

    Bioinformatics

  • Anirudh Narsipur
  • Joel Simonoff

    AI@LatchBio

  • Dianzhuo Wang
  • Evan Seeyave

    above average mango eater

  • Harmon Bhasin
  • Arjun Banerjee
  • Christopher Zou
  • Ramesh Ramasamy
  • Qian
  • Sean Poust
  • Alex Urrutia
  • Social

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