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Letters from a Zeneca

Zeneca

Weekly thoughts to help you build wealth through crypto, written by someone who has lost and made millions trading & investing

Platform
Substack
PricingFreemiumPublishesTwice weekly
Issues168SubscribersRead zeneca.xyz

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#22
Substack
/Crypto(Free)
#23
Substack
/Crypto(Paid)

Latest Issues

Recent posts by this newsletter. Browse the email archive.

Letter 110: The Great Rotation (Memes -> AI)

I’ve been banging the drum on AI being where some of the best opportunities in crypto are for years, with a renewed focus over these last few months. Back in Letter 93 I called x402 a “dark horse” for 2026. In Letter 95 I shared four low ca...

9 days ago
7
0

Letter 109: All About Local LLMs

I think this is one of the most practically useful things I’ve written in a while. Although once again not strictly crypto related, it is very much in line with my recent posts on AI agents and Claude Code that have been very popular.

15 days ago
6
0

Letter 108: What Are LLMs, and How Do They Work?

Alright people seem to be enjoying the AI content lately so we’re gonna keep it going. That said, the market is on the up and up lately so we gotta take a look at crypto again soon and see what’s worth paying attention to.

22 days ago
17
3

Letter 107: Setting Up an AI Agent

My brother is in town this week and he asked for my help setting up claude co-work. I had a friend reach out yesterday and ask me half a dozen questions about automating their workflow with AI: should they use openclaw? or hermes? or claude...

a month ago
19
2

Authors

The writers behind this newsletter.

  • Zeneca

    Ex-professional poker player turned crypto investor, sharing tips on making money and staying sane

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