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Mind & Matter

Nick Jikomes, PhD
Hundreds of paid subscribers

Weekly science podcast and essays by biologist Nick Jikomes, PhD. Researchers and scientists explain the brain, nutrition, metabolism, drugs and aging.

Platform
Substack
PricingFreemiumPublishesTwice weekly
Issues399Founded5 years agoLast Issue36 hours ago
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mindandmatter.substack.com
Artwork for Mind & Matter

Latest Issues

Mitochondria, Energy & Metabolic Health | Curated Content Bundle

Specific episodes and essays in a guided order, from mitochondrial basics to peptides, nutrition, and stress resilience in health & disease.

A guided path through Mind & Matter podcasts and articles on how your cells make, spend, and signa...

36 hours ago
6
Paid

Selenium Deficiency, Thyroid Health & Autoimmunity | Lutz Schomburg | Episode 308

How the micronutrient selenium work in the body, from oxidative stress management to thyroid health.

Wide release: Available for free by October 5, 2026, on Apple, Spotify, YouTube, etc.

5 days ago
Paid

HDL Cholesterol: What is “good” about it?

High HDL appears to blunt the risk that comes with high apoB, and its antioxidant role may explain why

M&M written content is human-created, independently researched, and filled with resources to deepen your learning. Click here to see all...

7 days ago
10
2
Paid

GDF15, Morning Sickness & Mitochondrial Stress | Stephen O’Rahilly | Episode 311

Stephen O’Rahilly explains GDF15, a hormone released when cells are under stress, why it makes people sick and eat less, and why the nausea of pregnancy comes from GDF15 made by the fetus.

Wide release: Available for free by November 3, 20...

9 days ago
2
Paid

Psilocybin vs. SSRIs for Depression, Emotional Blunting & How Psychedelics Work | Robin Carhart-Harris | Episode 310

How psychedelics work & how they compare to SSRIs in terms of depression and side effects.

Wide release: Available for free by October 26, 2026, on Apple, Spotify, YouTube, etc.

11 days ago
3
Paid

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Authors

The writers behind this newsletter.

  • Nick Jikomes, PhD

    Biologist and host of the Mind & Matter podcast. PhD in neuroscience from Harvard, BS in genetics from UW-Madison. Formerly in plant chemistry research and cannabis technology.

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