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Adith Arun

Writing about medicine, biology, stats, and anything in between. Commentary on new medical research, clinical trials, and biotech companies.

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Substack
PricingOnly free issuesPublishesWeekly
Issues24Founded5 years agoLast Issue2 months ago
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Latest Issues

Is there really a 400% increase in colorectal cancer incidence amongst children?

The uptick in early-onset (< 50 years old) colorectal cancer incidence has been a topic of much discussion and investigation. One striking observation is that in the US from 1999 to 2020, the incidence rate of colorectal cancers grew ~400%...

2 months ago
4
1

Trying to understand the Bundibugyo Ebola virus (and profiling what we do NOT know)

  1. Extent of the outbreak and historical context

  2. Estimating case fatality rates and reproductive number of the Ebola virus

  3. Clinical Course of Ebola

  4. Management of Ebola

  5. BDBV Clinical Course

  6. BDBV incubation peri...

2 months ago

What do we know about the 2026 Hantavirus outbreak?

An outbreak of hantavirus occurred on the MV Hondius, a cruise ship traveling from Argentina to Cape Verde, in late April/early May. As of May 13, 11 people have been suspected or confirmed to have the Andes Virus (ANDV), a strain of hantav...

3 months ago
1

Should we stop trialing relaxin drugs in pulmonary hypertension?

AstraZeneca’s phase 2 Re-PHIRE results in PH-HF

AstraZeneca ($AZN) tried a relaxin-mimetic (AZD3427) in patients with pulmonary hypertension associated with heart failure (PH-HF) in the phase 2b Re-PHIRE study. 220 patients were random...

3 months ago
6

Maybe, Maybe not

There is a 2nd century B.C. Chinese story that I enjoy. I first came across a modified version of it and so that’s what I will share here.1 It goes:

Once upon a time, there was a Chinese farmer who lost a horse. It ran away.
All his...

3 months ago
2

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