Nick Mark
Seattle intensivist blog
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 18 | Founded | 5 years ago | Last Issue | 7 days ago |
| Active | |||||
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nickmark.substack.comLatest Issues
Pacing the Frontier, or Pacing the Narrative?
On Saturday, Dario Amodei published an essay “We Must Pace the Frontier“ calling on AI companies to deliberately “slow the pace” at which they improve model capabilities. The framing, predictably, was existential: humanity needs time to cat...
The Hidden Costs of Fake Antibody Validation
Everyone who has worked in a lab has had the experience of buying a reagent that looks perfect in the manufacturer’s catalog only to have it fail repeatedly in your hands. The frustration of producing bad Western blots is a right of passage...
No, AI Didn't Just Cure Cancer
On August 19, 2026, Merck and Moderna announced via press release that the Phase 3 trial (INTerpath-001) of their personalized mRNA therapy intismeran autogene, combined with pembrolizumab, met its primary endpoint of recurrence-free surviv...
The Myth of the “72 Jabs”
“Kids today get 72 jabs” is an oft-repeated rallying cry among those virulently opposed to vaccines. Like most viral numbers, “72 jabs” has become a truism accepted unquestioningly by people who’ve never bothered to count. And much like the...
The Whole-Body MRI Industry's Liability Time Bomb
On July 15, 2023, a 37-year-old father of two named Sean Clifford paid $2,500 for an elective whole-body MRI at a Prenuvo clinic in Manhattan. The report came back clean: “No evidence of proximal intracranial arterial aneurysm.” Eight month...
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ICU & Lung Doc | Husband, Dad² | Passionate about improving medicine with #MedEd #POCUS #ML/#AI #MedTech #DadJokes | opinions = mine ≠ advice
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