Nick Mark
Seattle intensivist blog
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 20 | Founded | 5 years ago | Last Issue | 14 days ago |
| Active | |||||
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nickmark.substack.comLatest Issues
Lies, Damned Lies, and Log Scales
Mark Twain popularized the saying “Lies, damned lies, and statistics.” A common way that people lie with statistics is not with the math itself but with the visual display of information. One of the most damned lies I see is the misuse and...
Boats Against the Current: Gatsby, Sobotka, and the Failure of Reinvention in America
T. S. Eliot wrote, “Immature poets imitate; mature poets steal; bad poets deface what they take, and good poets make it into something better, or at least something different.” The criminally underrated second season of The Wire steals from...
Pacing the Frontier, or Pacing the Narrative?
On Saturday, Dario Amodei published an essay “We Must Pace the Frontier“ calling on AI companies to deliberately “slow the pace” at which they improve model capabilities. The framing, predictably, was existential: humanity needs time to cat...
The Hidden Costs of Fake Antibody Validation
Everyone who has worked in a lab has had the experience of buying a reagent that looks perfect in the manufacturer’s catalog only to have it fail repeatedly in your hands. The frustration of producing bad Western blots is a right of passage...
No, AI Didn't Just Cure Cancer
On August 19, 2026, Merck and Moderna announced via press release that the Phase 3 trial (INTerpath-001) of their personalized mRNA therapy intismeran autogene, combined with pembrolizumab, met its primary endpoint of recurrence-free surviv...
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ICU & Lung Doc | Husband, Dad² | Passionate about improving medicine with #MedEd #POCUS #ML/#AI #MedTech #DadJokes | opinions = mine ≠ advice
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