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Patriek Karayil on Substack

Patriek Karayil

Strategic Advisor, Office of the Secretary, HHS Former White House Presidential Innovation Fellow

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Latest Issues

Why Did It Take Decades to Question Psychiatric Drugs and the "Chemical Imbalance" Story?

What happens when the core narrative an institution presents to the public turns out to be fundamentally incomplete?

For decades, the public conversation surrounding psychiatric medicine rested on an elegantly simple premise: mental distre...

6 days ago

What STAR*D and WHO Data Reveal About Psychiatric Research

In millions of American households, a familiar story plays out. A family member struggles with chronic distress, enters the healthcare system, and receives an evidence-based diagnosis followed by a standard course of treatment. Yet years la...

7 days ago

What the Pediatric Antidepressant Record Reveals About How Medical Evidence Becomes Accepted

Most Americans will never read the clinical trials behind a prescription. They rely on a chain of trust: researchers generate evidence, regulators evaluate it, journals publish it, professional groups interpret it, and clinicians apply it....

8 days ago

From Roundtable to Reform: The Critical State-by-State Strategy to Make America Healthy Again

At the heart of modern public health lies a delicate, unspoken contract: the public yields a degree of individual autonomy to centralized institutions in exchange for safety, predictability, and evidence-based guidance.

When that contract...

a month ago

Three Questions This Measles Roundtable Raised for Healthcare Leaders

The question was not simply whether measles is dangerous. It was what healthcare leaders should do when parents fear both the disease and the intervention intended to prevent it.

That tension shaped a pediatric roundtable I moderated on me...

a month ago
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  • Patriek Karayil

    Strategic advisor and White House Presidential Innovation Fellow. Insights and analysis from expert interviews on healthcare, medicine, and public health.

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