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500 Rules of Cardiology

Paul D. Thompson, MD

These are not really "Rules" and not yet 500, but hopefully helpful principles I have used in teaching and practice over the 50+ years since I graduated from medical school.

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Latest Issues

Gastroenterology for Lipidologists and Cardiologists

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I saw a 76-year-old female for the first time on September 22, 2026 for management of high triglycerides (TGs). Her TGs had ranged between 254 to 377 mg / dl over the last several years.

Thanks...

5 days ago
16
3

More on Very High LDL Levels

Peri-orbital Xanthalasma in a Woman with Genetic Hyperlipidemia

My post on August 25, 2025 entitled “Causes of Extremely High LDL-C Levels” and subtitled “Include ‘Skinny’ Patients on Ketogenic Diet” was designed to highlight the principal...

12 days ago
6
8

Reducing Lipoprotein a Failed to Reduce Atherosclerotic Events

Reproduced from Tsimikas S. J Am Coll Cardiol. 2017 Feb 14;69(6):692-711.

Inflammation and lipoprotein a (Lpa) have been among the hottest topics in cardiology. My last post (1) discussed inflammation and the failure of a randomized contro...

19 days ago
17
12

What’s Hot – Inflammation; And What’s Not – Inflammation

We recently learned that two randomized controlled clinical trials (RCTs) addressing two of the hottest topics in cardiology, inflammation and lipoprotein a (Lpa), failed to reduce cardiovascular disease (CVD) events.

I am not surprised fo...

a month ago
15
8

Lifetime Achievement Award in Sports Cardiology

I am honored to be awarded the first-everLifetime Achievement Award from the Sports Cardiology Society. I am fortunate to have been able to combine my personal interests in exercise and sports performance with a career in clinical cardiolog...

a month ago
28
29

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  • Paul D. Thompson, MD

    Paul D. Thompson, MD is Chief of Cardiology-Emeritus at Hartford Hospital. He has authored over 500 articles & 3 books on exercise and cardiology. He qualified for the 1972 US Olympic Marathon Trials & finished 16th in the 1976 Boston Marathon.

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