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500 Rules of Cardiology

Paul D. Thompson, MD

These are not really "Rules" and not yet 500, but hopefully helpful principles I have used in teaching and practice over the 50+ years since I graduated from medical school.

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Substack
PricingOnly free issuesPublishesWeekly
Issues179Founded3 years agoLast Issue8 days ago
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Artwork for 500 Rules of Cardiology

Latest Issues

Nothing Cures Statin Muscle Complaints Like a Heart Attack

1970 - Ball State, Muncie, Indiana - L to Rt - David Costill, PhD, George Branan, MD, Ken Sparks, PhD, Craig Turner, Richard Bowers, PhD, Paul Thompson. Robert Gregor, PhD is the muscle biopsy subject.

I have had multiple patients who refu...

8 days ago
29
6

It’s Bogus to Use N-of-1 Studies to Prove that Statin-Induced Myalgia is BOGUS

My last several posts have summarized some of our studies on Statin Associated Muscle Symptoms (SAMS). Our studies show that statins produce muscle symptoms including myalgia and cramps in about 5% of subjects treated with the highest doses...

15 days ago
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2

STOMP - The Effects of STatins On Muscle Function and Performance

My last post discussed the debate as to whether or not statins cause muscle side effects. (1) This debate is between excellent researchers, who perform large, randomized controlled clinical trials of statins (the Cholesterol Treatment Trial...

22 days ago
45
14

The Risks & Benefit of Statin Treatment

Reproduced from Shutterstock Via Subscription

This is the fourth post in a series on how statins affect skeletal muscle. The previous three were published on Substack on April 14 (1) , April 21 (2), and April 28, 2026.(3)

Thanks for readi...

a month ago
61
14

The 4 T's - Teaching Teaches the Teacher

Drawing Reproduced from the Web in commemoration of Dr. Braunwals’s Receiving the 2002 King Faisal Prize in Medicine

Dr. Eugene Brauwald died on April 22, 2026 at age 96. His contributions to cardiology are extraordinary. This article was...

a month ago
35

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  • Paul D. Thompson, MD

    Paul D. Thompson, MD is Chief of Cardiology-Emeritus at Hartford Hospital. He has authored over 500 articles & 3 books on exercise and cardiology. He qualified for the 1972 US Olympic Marathon Trials & finished 16th in the 1976 Boston Marathon.

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