Progressions: A deep look at prostate cancer
Ben NathansonDeep dives on prostate cancer, patient to patient. How do our treatments work? How do they fail? What might be next for research?
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Meet the androgen receptor
Like many complex proteins, the androgen receptor distributes its duties over sections called domains, and this is its org chart. The ligand binding domain is where testosterone binds. The DNA binding domain rests directly on DNA for transc...
Am I dying, or aren’t I?
When we aren’t being treated, we’re being tested. We rely on testing almost as much as we rely on our drugs.
We wish these tests were all-seeing and all-knowing, but often they’re more like getting directions from a geezer on his front po...
Hazard ratios clarified
Hazard ratios are a souped-up version of a simpler comparison. Understanding that simpler comparison gives the essence of HR. I’ve added a section, The intuition, to the original post to explain it.
It just don’t work on you
In the blues stomper Got My Mojo Workin’, Muddy Waters shouts:
Text within this block will maintain its original spacing when published
Got my mojo working,
Got my mojo working,
Got my mojo working, but it just don’t...
Genes? Chromosomes? DNA?
You remember genes and chromosomes vaguely from biology class and you’ve seen more than enough DNA helixes.
If you wonder how genes, chromosomes, and DNA fit together, this post is for you.
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Where’s my DNA?
Nearly all your...
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Authors
The writers behind this newsletter.
Gleason 8 ductal prostate cancer; prostatectomy and salvage radiation; lung mets. I aim to contribute to the prostate cancer community and speak out on its behalf. In working life I was a research engineer and a journalist.
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