Scaling Biotech
Jesse JohnsonExploring how big pharma partners with AI startups to build internal capabilities, data and models
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 267 | Founded | 6 years ago | Last Issue | 7 days ago |
| Active | |||||
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scalingbiotech.substack.comLatest Issues
MCP is the new SaaS
One question that keeps coming up in my conversations about building Data Operations Plans is how AI tools like Claude Cowork might fit in. Many teams outside biopharma are using a protocol called MCP that lets them connect external tools l...
We won't know when AI solves drug discovery
Last week, I wrote a relatively optimistic post about how AI could potentially address what I see as one of the most fundamental issues in drug discovery, the clinical information bottleneck. This week’s post is going to be a bit more pessi...
The Clinical Information Bottleneck
In a few posts now, I’ve referred to this idea I call the “Clinical Information Bottleneck.” The idea is kind of abstract, but I think it’s at the heart of the rising cost of drug development, and clearing this bottleneck will be key to how...
Paired assays and the clinical information bottleneck
Here’s another one in the category of “assay types matter less than you might think”: NOETIK recently published a blog post announcing that their new foundation model, TARIO-2 can predict spatial transcriptomics values from routinely collec...
Say good bye to single-assay training datasets
A few times in recent posts, I’ve claimed (without evidence) that bio foundation models can be trained on readouts from different kinds of assays to create a single model that’s more powerful than you could’ve gotten from any one assay alon...
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