Reletter
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For people curious about the brain and human nature

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Substack
PricingOnly free issuesPublishesWeekly
Issues52Founded6 years agoLast Issue10 months ago
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Artwork for Synapse

Latest Issues

From "Synapse" to "Overfitted"!

Hey Synapse readers!

I’ve launched a new newsletter called Overfitted, my attempt to cut through the noise in evidence-based medicine. We’ll dissect studies, challenge assumptions, and debate ideas—mostly in Neurology and Alzheimer’s, tho...

10 months ago
2

I was wrong about twin studies

In the past few weeks I’ve enjoyed digging into Kathryn Paige Harden’s The Genetic Lottery and, thanks to Kathryn’s eloquent and clear writing, realized that I misunderstood how ‘twin studies’ have been used to understand the role of geneti...

5 years ago
7
1

Our Genetic Lottery

It has been a couple of weeks since I was last in your inbox and this is because I’ve been struggling to grapple with my recent inquiry into behavioral genetics. Last month, I wrote a short introduction to behavior genetics in which I intro...

5 years ago
5
1

Some neuroscientists are confused

This summer, I wrote a series of stories about the Thousand Brains Theory of Intelligence which postulates that the neocortex is subdivided into hundreds of thousands of cortical columns which each build models of the world and work togethe...

5 years ago
5
1

How does your DNA determine who you become?

I’ve been thinking a lot lately about the control we have over who we become. I’ve recently made a more concerted effort to reflect on my own character, how it has changed over time, and how it interacts with other people. A big part of tha...

5 years ago
4
1

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  • Clayton Mansel

    MD/PhD student studying the utility of genomic-informed risk assessments for dementia \ud83e\udde0\ud83e\uddec | Strong Towns Advocate \ud83c\udfd9️ | Author of Overfitted \ud83d\udcca

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