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The Binding Site

Madhuri Manohar, PhD

Curation of practical knowledge of antibodies for the next generation of researchers, along with current research developments. Research Scientist with a Cambridge PhD. Powered by coffee, curiosity, and clean data.

Platform
Substack
PricingOnly free issuesPublishesTwice weekly
Issues19Founded5 months agoLast Issue7 days ago
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Latest Issues

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Navigating the demands of a PhD program is a monumental task, but understanding how to carve out a good life outside of the lab can often feel even more elusive. When I was reflecting on this to write an article, I almost felt I wouldn’t be...

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Welcome to the seventh edition of the ‘The Binding Brief’, a weekly newsletter dropping in your inbox every Wednesday where we shall journey together into the world of antibodies.

This week, we have some exciting things to discuss.

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100 Days on Substack

This week, I crossed the 100-day milestone on Substack. If you had asked me on the morning of March 24, 2026, if I could imagine writing this post today, I would have scoffed. I am the queen of having too many interests, but I’ve lacked the...

18 days ago
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V(D)J Recombination and Antibody Diversity Part 1

Disclaimer: This is a fictional piece written from the perspective of Professor Susumu Tonegawa. Much of the content and facts are drawn from his Nobel Prize lecture and interviews online. I've taken the liberty of adding some fictional ele...

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The Binding Brief: Over-glorifying AI-designed proteins, more protein-related happiness, and Antibody-Drug Conjugates

Welcome to the sixth edition of the ‘The Binding Brief’, a weekly newsletter dropping in your inbox every Wednesday where we shall journey together into the world of antibodies.

First off, I wanted to address my wins of the week. Thank you...

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  • Madhuri Manohar, PhD

    Research Scientist from Cambridge powered by coffee, curiosity, and clean data. I study antibodies for a living and write about what they teach us.

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