The Binding Site
Madhuri Manohar, PhD, Christos Efthymiou, PhD, Deep Shikha, PhDPractical antibody science for early-career researchers and PhD students, from understanding and building antibodies to reading the data and engineering them for purpose. Powered by coffee, curiosity, and clean data.
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 32 | Founded | 9 months ago | Last Issue | 17 days ago |
| Active | |||||
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thebindingsite.substack.comLatest Issues
Getting to Know the Single-Chain Variable Fragment (scFv)
It was around month 10 of my PhD. I had just got back into the lab after the pandemic, and all the restrictions surrounding it had kept me away from my lab bench.
We were still working at half capacity, which meant that if I was in the lab...
#02: If we were having coffee, I would tell you...
Dear , I hope everything is well in your corner of the world. ☕️ Welcome to “Mocha with Madhuri” and to the second installment of our coffee chats.
This is probably my favorite kind of article: a space where I can share personal updates, l...
I Thought This Man Was a Fool
Photo by Ed Robertson on Unsplash
What can an 1889 Russian short story teach us about becoming a better scientist?
It turns out… quite a lot!
If you’d asked my younger self what my favorite subject was, I wouldn’t have hesitated:...
Growing on Substack as a Science Communicator
Doing laundry at 11 pm on a Sunday night can be really beneficial.
It was March 2016. The winters in Baltimore were just about dying down. I found myself in the basement of my 11-storey apartment, with my white, netted plastic tub filled w...
A Specific Antibody Is Not Necessarily Accurate for Studying Protein Localization
Today, The Binding Site is lucky to have guest-write an article for me. Bihar to Bethesda, Deep was born in a small town in Bihar, India, where "scientific research" wasn't really a career option, and things were a bit difficult for women....
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Authors
The writers behind this newsletter.
Scientist, Educator & Digital Writer. I write about antibody development and engineering for early-career researchers, helping you understand the science, design better experiments, and troubleshoot with confidence.
I love writing about how people build careers, how institutions shape ambition, why so many highly capable people end up feeling lost, and how science, AI, media, and work are all changing at the same time.
Neurobiology Postdoc at NIH, USA | From Bihar 🇮🇳 | Learning to think and live freely 🌊
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