The Biotech Capital Compass
Biotechnology & ‘Fog of Valuation’ savant
| Platform |  | Pricing | Freemium | Publishes | Daily |
|---|---|---|---|---|---|
| Issues | 232 | Founded | 2 years ago | Last Issue | 4 days ago |
| Active | |||||
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hartajsingh1.substack.comLatest Issues
The Biotech Capital Compass: August 2026 in Review
From the Editor’s Desk
August began with a question left over from July.
Biotechnology had experienced another sharp pullback, yet many of the industry’s underlying fundamentals appeared considerably healthier than they had during the...
Video Companion: Understanding Short Interest in Biotechnology
Short interest is widely discussed in biotechnology investing, but the mechanics—and what the signal actually means—can sometimes be misunderstood.
In this Free Video Companion, we break the concept down from first principles: how an inves...
Tape Check: A Year Can Change a Lot
Biotech has substantially outrun broader markets. We examine the technical signals, improving fundamentals and remaining risks underneath a remarkable twelve-month recovery.
I. Introduction
Video Recap: Six Months That Tested Biotech — Revisiting 1H 2025
The first half of 2025 was a difficult period for biotechnology investors. After entering the year with cautious optimism, the XBI repeatedly attempted to recover, only to be confronted by regulatory uncertainty, policy concerns, weak capit...
The Long Climb: Assembly Biosciences Builds the Bridge
After clinical setbacks, Assembly rebuilt around antiviral science, Gilead partnership economics and financial runway. Now the science must validate the strategy.
Assembly Biosciences (NASDAQ: ASMB) has traveled a considerable distance fro...
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Authors
The writers behind this newsletter.
Biotech Capital Compass breaks down complex biotech stories into valuation, risk, and narrative frameworks investors can use. Written by Hartaj Singh, a biotech analyst focused on translating innovation into investment reality.
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