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The Biotech Capital Compass

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Biotechnology & ‘Fog of Valuation’ savant

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Latest Issues

The Long Climb: Assembly Biosciences (ASMB) — What Comes After the Bridge?

The Gilead partnership helped Assembly rebuild. Now ABI-6250, its proprietary pipeline and capital allocation must show where that bridge ultimately leads.

Several weeks ago, we examined how Assembly Biosciences rebuilt itself following th...

7 days ago
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Video Companion: Reading the Signals as Biotech Normalizes

Biotechnology is sending investors a complicated collection of signals.

M&A remains active. The IPO market is reopening selectively. Biotech specialist investors appear to be generating better returns. At the same time, Treasury yields hav...

8 days ago
1

Video Recap: Is Biotechnology Beginning to Feel Normal Again?

After two difficult years, biotechnology increasingly appears to be behaving more like a functioning capital market again—not uniformly strong or free from risk, but selective, differentiated, and increasingly focused on execution.

In this...

10 days ago

The Biotech Exchange: Moderna, INT and the Next Test for Personalized Cancer Therapy

This conversation was originally published by Katerina at Biotech Blueprint, and we are pleased to republish it here for Biotech Capital Compass readers.

Katerina and I approach biotechnology from somewhat different perspectives, which is...

12 days ago
1

The Expectations Game: Playing Biogen’s Hand

Biogen’s business is improving, but five approaching Phase 3 readouts test how investors should value opportunity before the cards are revealed.

Biogen’s operating picture has improved considerably since our May 2026 update. The Apellis ac...

14 days ago
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  • The Biotech Capital Compass

    Biotech Capital Compass breaks down complex biotech stories into valuation, risk, and narrative frameworks investors can use. Written by Hartaj Singh, a biotech analyst focused on translating innovation into investment reality.

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