The Hard Thing
Anna Marie WagnerMusings about how sh!t gets done.
| Platform |  | Pricing | Only free issues |
|---|---|---|---|
| Publishes | Weekly | Issues | 7 |
| Subscribers | Read | thehardthing.substack.com |
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Latest Issues
Recent posts by this newsletter. Browse the email archive.
LMGTFY: A primer on therapeutics R&D
Biotech is the WORST industry for jargon - it reinforces siloes and makes outsiders feel unwelcome...
The Hard Thing #5: The Myth of Platform Biotech
Biology is the most powerful technology on the planet (come at me, bros).
Sneak peek: the definitive AI x Bio database
2025 is a new year and I decided it was time to brush off some old skills and learn some new ones. I wanted to play around a bit with practical AI-assisted information retrieval and dust off some very rusty coding skills and so I decided to...
Hard Thing #4: The 10x Mentor
“I want to be you when I grow up…” I said, clarity unexpectedly dawning on me (a few years ago, at an age at which I fully expected to have been “grown up”).
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Authors
The writers behind this newsletter.
Trying to set a good example for my kids: working hard on problems worth solving.
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