The Hard Thing
Anna Marie WagnerMusings about how sh!t gets done.
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 11 | Founded | 2 years ago | Last Issue | 4 months ago |
| Active | |||||
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thehardthing.substack.comLatest Issues
On Observability
The Almost Perfect Game
On June 2, 2010, Armando Galarraga took the mound for the Detroit Tigers. At 28, the Venezuelan pitcher was fighting to stay relevant after coming off a rough season. Nearly three hours later, at the top of the...
Hard Thing #7: The BS Umbrella
I recently had a VC describe the Founder/CEO job to me as the “bullsh!t umbrella” - the job is to prevent the BS from reaching the rest of the team.
The team is precious - they are the biggest investment a Founder/CEO makes. The Founder/CE...
Hard Thing #6.2: Hundreds of daily decisions
A fun thing to do with young kids (or students in an intro to CS class) is to ask them to explain how to do simple tasks in the excruciating detail required to actually do them.
How do you make a peanut butter sandwich? Well…put the peanut...
Hard Thing #6.1: Taste All the Way Down
Oscillator and The Hard Thing are blogs by people who have spent many years thinking together about the applications and implications of new technologies in the business of biology. We’re teaming up for a series of posts about AI, biotech,...
LMGTFY: A primer on therapeutics R&D
Biotech is the WORST industry for jargon - it reinforces siloes and makes outsiders feel unwelcome...
Remember the old "Let me Google that for you" meme? ChatGPT (and other tools) makes that so much more relevant today and it's still...
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Authors
The writers behind this newsletter.
Trying to set a good example for my kids: working hard on problems worth solving.
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