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The Last Great Mystery

Arye

Transformation and transcendence through biotechnology

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Substack
PricingOnly free issuesPublishesMonthly
Issues45Founded6 years agoLast Issuea month ago
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Latest Issues

Zymergen’s final fallout

Zymergen was once the darling of Silicon Valley synthetic biology companies, with over $1b raised from 2013 to 2020, including more than $400m from Softbank. They marketed themselves as “molecular technology” for the “next industrial revolu...

a month ago
27

Hype and hope at SynBioBeta 2026

SynBioBeta is the premier annual conference for the synthetic biology industry. I’ve been to many of them over the years, but it had been 4 years since my last one. In the Spring of 2022 we were at the tail end of the ZIRP era, though maybe...

5 months ago
15
2

Talking to Cetaceans

One of the great pleasures of living in California is being able to enjoy the ocean all year round. And one of the greatest gifts when spending time in the water is interactions with our native dolphin population - sitting in the lineup wai...

9 months ago
3

Biotech's fabless future

just add bioreactors

Most of the leading, scaled companies in industrial biotech are highly vertically integrated. Those who sell the molecules make the molecules too (DSM, IFF, BASF, to name a few). There are a few reasons this is the cas...

a year ago
22

Making Biomanufacturing Great Again

Had a great time chatting with Brom and Sam from XEIA Venture Partners about Biosphere, the state of the biomanufacturing industry, and other weird stuff (remote viewing, cetacean consciousness, Peter Thiel). Enjoy !

a year ago
4

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  • Arye

    Biotechnologist, company builder, and investor. Currently building Biosphere, to unleash the industrial biotech industry.

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