The Oncology Shot with Timothee Olivier
Timothée Olivier, Sahar van Waalwijk, Marco Donia, Yago GaritaonaindiaMy Personal Substack
| Platform |  | Pricing | Only free issues | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 37 | Founded | a year ago | Last Issue | 16 days ago |
| Active | |||||
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theoncologyshot.comLatest Issues
A Cultural Gap: How Many Patients With Metastatic Pancreatic Cancer Do Not Start Systemic Therapy?
My attention was recently drawn to two real-world studies.
The first is coming from the Netherlands, published in the European Journal of Cancer. The full article is available here. In their work, Broekman et al. wanted to identify factors...
“Chemo‑free” is not always better: the FDA withdrawal of adagrasib in colorectal cancer
We have all heard the powerful marketing phrases “chemo-free” and “targeted therapy.” They sound modern, precise, and less toxic. Regulators are willing to grant accelerated or conditional approvals on the basis of response rates for such t...
Daraxonrasib Is FDA-Approved: Both Good News and Bad News
Daraxonrasib is an oral RAS(ON) multi-selective, non-covalent inhibitor. In RASolute 302, the product was tested in the second-line setting of patients with metastatic pancreatic cancer, with a median survival gain from 6.7 to 13.2 months....
Beyond Cross-Trial Comparisons: What Digitized Survival Curves Can Really Tell Us
In today’s guest post, it’s my great pleasure to welcome Yago Garitaonaindia and Marco Donia. The power of reconstructed datasets from published curves cannot be overstated. In a series of three peer-reviewed 2026 publications, they demonst...
Sham Controls and Tumor Treating Fields: Does the Ethical Argument Hold?
Today, we are covering our new work just published in The European Journal of Cancer, entitled “Tumor treating fields: Will the evidence gap ever be filled?”. We thank our co-authors Sruthi Ranganathan, , and Alessandro Hammond!
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Authors
The writers behind this newsletter.
Swiss oncologist at Geneva University Hospital. Research on trial methodology, health policy, and critical appraisal. I joined Vinay Prasad’s research lab in November 2021. Geneva Ethics Committee. Co-EiC ESMO Rare Cancers. No COI. Views mine.
Pharmacist Medicine & Society (PharmD-PhD), National Funder’s Committee for Evaluation of Specialised Medicines and Companion Diagnostics, CZ. Associate Professor of Medical Oncology, focused on Access to Medicines, LUMC, NL
Clinician-Scientist, Oncologist, Professor of Immuno-Oncology National Center for Cancer Immune Therapy, Department of Oncology, Copenhagen University Hospital, Herlev, Denmark
Medical Oncologist and Translational Researcher, National Center for Cancer Immune Therapy, CCIT-DK, Copenhagen University Hospital, DK.
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