The Pattern Project - Low Dose 5-MeO-DMT Research Collective
The Pattern Project, Ari FranklinThe first and only collective focused exclusively on the potential of low dose 5-MeO-DMT. Subscribe to learn about new applications, protocols, and research reports.
| Platform |  | Pricing | Freemium | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 52 | Founded | 3 years ago | Last Issue | 6 days ago |
| Active | |||||
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patternproject.substack.comLatest Issues
Low-5 and the Undefended Leader
Every group runs two conversations at once: the one being spoken, and the one being felt. In our age of dizzying complexity, we need leaders who can be in touch with feeling as much as doing.
A new paper – Attunement as Leadership: Council...
Quarter Notes: The Top 5-MeO Stories of Q1,2026
Quarter Notes is our new quarterly roundup: the research, the news, and the Pattern Project stories that moved the needle this quarter.
March 2026
Inhaled 5-MeO-DMT Produces Strong Remission Rates in Treatment-Resistant Depressio...
Top Takeaways From Exploring Patterns: A Survey of Low-5 Experiences
Our latest report, Exploring Patterns: A Survey of Low-5 Experiences, draws on our study of 68 adults experienced with psychedelics and meditation who had used Low-5 in the past week. Recruited through psychedelic community channels, partic...
Exploring Patterns: A Survey of Low-5 Experiences
Contents
I. Summary
II. Background
III. Methods
IV. Findings
V. Interpretation
I. Summary
Background: Low-5 has been described by users as distinct from high-dose 5-MeO-DMT, with potential applications for meditation and t...
What Low-5 Practitioners Want to Know
We asked 62 practitioners currently using Low-5 with clients to tell us what they want to learn. Here is what we learned.
Low-5 is Very New to Most
The gap between respondents’ years of broader professional experience and Low-5-specific e...
Key Facts
Audience Metrics
Subscribers, engagement, traffic and sponsorship for The Pattern Project.
| Subscribers | Engagement | 73 | Monthly Web Visits | ||
|---|---|---|---|---|---|
| Accepts Sponsors | Estimated Cost per Ad | ||||
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Authors
The writers behind this newsletter.
A collective of mental health researchers, therapists, meditators, and innovators based in Canada. The organization is the first dedicated to exploring the breakthrough potential of combining mindfulness and other practices with Low-5.
Science Lead of The Pattern Project
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