This Week in Startups Newsletter
This Week In, [email protected]The definitive briefing for founders building companies, and the operators and investors who make it possible.
| Platform |  | Pricing | Only free issues | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 73 | Founded | 4 years ago | Last Issue | 8 days ago |
| Active | |||||
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twistartups.substack.comLatest Issues
Ask Jason: AI Extinction, Grok's Rogue Meme Coin & Weed Farms as Data Centers | E2337
This Week In Startups is made possible by:
Quo: http://quo.com/TWiST
The Conservation Fund: https://conservationfund.org
CLA: https://app.notion.com/p/withyou-help-eb83a84d32cf43f59af13cb11e2f56c3?source=copy_link
Tod...
3 very different takes on staffing decisions
Founders are getting a variation of this question in every meeting and interview: does AI mean your team gets BIGGER? Or smaller? While many of the answers will rely on “vibes,” at TWiST, we prefer a data-based approach.
Here’s a compellin...
The Pentagon Wants Equity in AI Startups | E2336
This Week In Startups is made possible by:
DigitalOcean — Want to see what building on a true AI-native platform looks like? Head to do.co/twist to start building on DigitalOcean’s AI-Native Cloud today — and cut your AI workload costs...
Tactical/Practical: It’s not just testing, it’s HOW you test
Businesses run on good data, so relentlessly testing your product is a crucial part of being a founder. But running a good experiment is more complex than just shipping variants, then looking at a dashboard to see which numbers go up.
On...
Tactical/Practical Tip of the Day: Talk to Everyone
“If AI takes all the jobs, what’s left for humans to do?” is a common refrain in 2026. In truth, AI agents are great at some things, and not-as-great (or even terrible) at others. Smart founders delegate tasks to agents at which they excel,...
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Authors
The writers behind this newsletter.
Podcasts and newsletters covering tech, startups, founders, venture capital, and AI from Jason Calacanis and LAUNCH
Founder, angel investor, & podcaster calacanis.com // [email protected] // X.com/jason Instagram.com/jason
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