Thrombo Trial Files
TrialFilesFree bimonthly newsletter that summarizes the most significant, practice-changing hematology randomized controlled trials, straight to your inbox.
| Platform |  | Pricing | Only free issues | Publishes | Monthly |
|---|---|---|---|---|---|
| Issues | 39 | Founded | 3 years ago | Last Issue | 3 months ago |
| Active | |||||
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thrombotrialfiles.substack.comLatest Issues
Thrombo Trial Files Throwback Thursday: TXA in Noncardiac Surgery, Liver Resection, and TBI
Tranexamic Acid in Patients Undergoing Noncardiac Surgery
Devereaux PJ et al. NEJM (April 2022)
Bottom Line: This randomized, double-blind, placebo-controlled trial enrolled 9535 patients undergoing noncardiac surgery and assigned the...
Thrombo Trial Files: Aspirin in CCS & Oral Anticoagulation, DOACs vs. Dual Antiplatelet Therapy Following LAAC, and Anticoagulation +/- CAVT in PE
Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation
Lemesle G et al. NEJM (August 2025)
Bottom Line: This multicenter, double-blind, randomized, placebo-controlled trial conducted in France involved 872 p...
Thrombo Trial Files Throwback Thursday: Rosuvastatin for VTE Risk in Cancer, E-Alerts for VTE Prophylaxis, and Thrombophilic Defects on Recurrent VTE
Effect of rosuvastatin on risk markers for venous thromboembolism in cancer
Ades S et al. Journal of Thrombosis and Haemostasis (June 2018)
Bottom Line: This was a double‑blind, crossover RCT evaluating whether rosuvastatin reduces bi...
Thrombo Trial Files: LMWH +/- ICD for VTE in Neurosurgical Procedures, U/S Screening for DVT in the ICU, and Apixaban vs. No Anticoagulation in ALL or Lymphoma
Intermittent compression devices as antithrombotic strategy in neurosurgical interventions
Zhang Z et al. Journal of Thrombosis and Haemostasis (November 2025)
Bottom Line: This randomized clinical trial assessed the effectiveness of...
Thrombo Trial Files Throwback Thursday: Warfarin Prophylaxis in Hop or Knee Arthroplasty, Enoxaparin in Hospitalized Patients with Cancer, and Rosuvastatin on Thrombin Generation
Effect of Low-Intensity vs Standard-Intensity Warfarin Prophylaxis on Venous Thromboembolism or Death Among Patients Undergoing Hip or Knee Arthroplasty
Gage BF et al. JAMA (September 2019)
Bottom Line: This was a multicenter, open-la...
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Free biweekly newsletter for trainees and staff on General Internal Medicine at Sinai Health that summarizes the most significant, practice-changing randomized controlled trials, straight to your inbox.
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