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Vinay Prasad's Observations and Thoughts

Vinay Prasad
Thousands of paid subscribers

Dr Prasad is a physician, professor, writer, and former senior government official.

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Substack
PricingFreemiumPublishesDaily
Issues502Founded6 years agoLast Issue2 days ago
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Latest Issues

Alcohol study started by Biden, buried by Trump, is finally published

A controversial study has at last been published. Commissioned by the Biden administration, ignored by the Trump administration, a paper on alcohol’s health effects finally sees the light of day.

The media is setting the narrative as you...

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Do GLP-1 drugs reduce the risk of cancer?

A new observational study— using “target trial” emulation— claims that in 2 years, GLP-1 lower the risk of cancer. It is being widely celebrated online. Bye bye myeloma, the authors would have you believe. Take a look.

Yet, strangely, thes...

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OpenEvidence reports that, as of May 2026, two-thirds of US physicians are using their platform. OpenEvidence provides a free service where doctors can ask clinical questions, and makes ends meet by showing targeted advertisements from the...

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Progress in oncology: a tale of two graphs and two diseases

Recently a post went viral showing progression free survival over time in multiple myeloma.

Recently a post went viral showing progression free survival over time in multiple myeloma.

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Daraxonrasib in pancreas cancer.

RASolute 302 trial has rightly generated significant excitement at ASCO2026 and I share this excitement. Pancreatic cancer has for long been a challenge for oncologists and KRAS is the classic ‘undruggable’ target. Any advance here is notab...

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