Zendudest’s Substack
ZendudestMy personal Substack
| Platform |  | Pricing | Only free issues | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 53 | Founded | a year ago | Last Issue | 6 days ago |
| Active | |||||
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zendudest.substack.comLatest Issues
Pharmaceutical companies are not hiding breakthrough treatments
I periodically share a cigar with a good friend of mine who recently shared his concern that:
The cures are out there—pharmaceutical companies are hiding them to make $$
Core claim: A cheap, effective, often “natural” or unpatentable cu...
'Curing' brain diseases
I’m attending an amazing meeting on Parkinson’s Disease sponsored by ASAP (Aligning Science Across Parkinson’s) and, of course, treatment/cure of PD is a yuuge theme. ‘A long time ago in a galaxy far, far away’ my lab invented DREADDs—the m...
In praise of Tom Insel and the NIMH
Much has been written, some of it by Tom, on his legacy at NIMH. Most of it negative. There is a recent substack which lays it out in great detail and I’ll give you my unvarnished perspective.
Yes, in retrospect we probably could have:...
What's up with Ibogaine?
”In the Gabonese night there is an initiatory world that never sleeps. It is the world of the Bwiti”
I’m sure anyone (well at least most of y’all) knows about ibogaine. If not, read the link above.
I returned late last night from a marvel...
AI meets Drug Discovery: Part Deux
In the first part of this series, I described the generic drug discovery pipeline and showed where AI might be useful (or useless). A particular area I would like to highlight here is the “PROTEIN ISOFORM PROBLEM”
Here’s the issue: a sing...
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