Zendudest’s Substack
ZendudestMy personal Substack
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 58 | Founded | a year ago | Last Issue | 3 days ago |
| Active | |||||
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zendudest.substack.comLatest Issues
From yeast to humans
In the early 1990’s my lab was devoted to understanding how clozapine achieved it’s remarkable efficacy in treatment-resistant schizophrenia and I was fortunate enough to be recruited to CWRU by Herbert Yale Meltzer (don’t you love his midd...
The joys of being a CRO for the NIH: Part 2
So to continue…by virtue of what I now recognize as a grand cosmic joke my lab was fortunate enough to obtain our FIRST NIH CONTRACT in 1998. Per his promise my former chair—the amazing Richard Hanson (may his memory be a blessing)—gave me...
Why you should consider being a CRO for the NIH: Part 1
My decades of zen training have alerted me to a “disturbance in the force” related to a recent exhortation regarding scientific excellence and the role of government in acclerating discoveries where they highlight the potential/real advanta...
When do I use AI and why?
As I mentioned previously, AI shows promise for therapeutic drug discovery in terms of ligand discovery and design, but will have challenges related to predicting clinical trial results and indications.
My lab uses AI-esque approaches con...
What is pharmacology?
Here at UNC we are in the midst of a search for a new Chair for the Department of Pharmacology. In fairness to the applicants, I’ll not comment on anything related to their presentations. I note that all are required to present a ‘Vision fo...
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