
Evidence without Agenda
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| Issues | 21 | Founded | 7 months ago | Last Issue | 9 days ago |
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The recently published SAKK 08/14 trial evaluating metformin in metastatic castration-resistant prostate cancer caught our attention because, once again, the results were negative.
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The phase 3 KEYNOTE-905 (EV-303) trial reports something the field has been waiting for: a clear survival benefit with perioperative systemic therapy in patients with muscle-invasive bladder cancer who are...
PEACE-3 is a randomized phase III trial evaluating whether the addition of radium-223 to enzalutamide improves outcomes in patients with metastatic castration-resistant prostate cancer (mCRPC) and bone metastases. Patients were assigned to...
Hot flushes remain one of the most persistent and impactful side effects of androgen deprivation therapy (ADT). Nearly every man treated will experience them, and yet we still do not have a universally accepted, well-tolerated, and effectiv...
The long-term outcomes of the HYPO-RT-PC trial were recently published in The Lancet Oncology.
The headline result is clear: ultra-hypofractionated radiotherapy demonstrates noninferiority to conventional fractionation f...
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The writers behind this newsletter.
Urologist - robotic surgery
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