Sensible Medicine
Sensible Medicine, John Mandrola, Vinay Prasad MD MPH, Adam Cifu, MD, Dr. Lucy McBride, Andrew J Foy, Against Medical Advice, Alex Lickerman, MDCommon sense and original thinking in bio-medicine
| Platform |  | Pricing | Freemium | Publishes | Daily |
|---|---|---|---|---|---|
| Issues | 1064 | Founded | 4 years ago | Last Issue | 2 days ago |
| Active | |||||
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sensible-med.comLatest Issues
Is an mRNA vaccine the best way to treat melanoma? We don’t know.
Last week, the news media and internet were abuzz about a trial conducted jointly by Moderna and Merck. The study compared a combination of pembrolizumab and an mRNA-based individualized neoantigen therapy with pembrolizumab alone in treatm...
Guidelines: The Good, the Bad, the Ugly
Guidelines have become ubiquitous. In 2024, 289 guidelines were published in the United States, a 29% increase from 2023, with the American Society of Clinical Oncology leading the list with 19. They are influential, often driving citations...
This Fortnight in Medicine XXXIII
Coronary-Artery Revascularization before Elective Major Vascular Surgery
Discontinuation of statins for primary prevention of atherosclerotic cardiovascular disease in adults aged 75 years or older (SAGA/SITE): a multicentre, open-label, p...
Lecture 4 - How not to be fooled
I notice that someone was angry that we are re-posting old episodes BEFORE we post the new ones. Just a reminder, we said we would do this! We will make the old ones available for free, and then post the new ones. Bear with us.
In the mean...
Choosing the Wrong Patient When it Comes to Left Atrial Appendage Closure
Many of you know that I am not convinced that percutaneous left atrial appendage closure benefits patients. The six trials against standard oral anticoagulation (OAC) simply do not reveal a net benefit in stroke reduction or bleeding.
But...
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Authors
The writers behind this newsletter.
Heart rhythm doc, writer/podcaster for @Medscape, learner, cyclist, married to an #HPM doctor. #MedicalConservative. The more you see, the harder medicine gets
Hematology Oncology Medicine Health Policy Epidemiology Professor
Internist, professor, patient. Author: Ending Medical Reversal; Symptom to Diagnosis; Sensible Medicine. Podcasts: S2D & Clinical Excellence.
Primary care doctor & bestselling author here to dispense fact-based, practical advice that fits your life. Health isn't about having all the answers; it's about asking better questions—of yourself, and of the people responsible for your care.
Associate Professor of Medicine and Public Health Sciences at Penn State Hershey Medical Center and College of Medicine
I am an internal medicine physician, teacher and writer. I write about the human side of medical care, paradoxes in medicine, and how to improve education. I am currently working on a book about the strange science of blood pressure.
Former faculty at the U of C, now running a direct primary care medical practice called KerixHealth.
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