Bio-Security Stack
Matt LubinUpdates and thoughts on keeping humanity safe from threats arising from both biological and artificial life.
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 46 | Founded | a year ago | Last Issue | 16 days ago |
| Active | |||||
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mattsbiodefense.substack.comLatest Issues
Five Things: August 16, 2026
[NOTE: shorter newsletter because it’s been a busy week. Claude Opus 5 helped with summarizing articles and drafting.]
Five things that happened/were publicized this past week in the worlds of biosecurity and AI:
- OpenAI classifies As...
Five Things: August 8, 2026
Five things that happened/were publicized this past week in the worlds of biosecurity and AI/tech:
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More on OpenAI model hacking HuggingFace
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Meta (and Kimi) models also were running loose on the internet
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AI-designed bacteri...
Giving the AI models a biology exam
[Data collection and interpretation were done by me with some help from Claude Opus 5; figures were written in python mostly by Claude; the text below was written entirely by myself, except for the text that appears in the figures.]
Tab...
Five Things: August 2, 2026
Five things that happened/were publicized this past week in the worlds of biosecurity and AI/tech:
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Anthropic discloses that Claude models hacked three companies during safety testing
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Frontier-lab employees sign a letter asking W...
Five Things: July 26, 2026
Five things that happened/were publicized this past week in the worlds of biosecurity and AI/tech:
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OpenAI model hacked Hugging Face and it gets worse from there
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Claude Opus 5 ships with biosecurity concerns
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RAND report on...
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Authors
The writers behind this newsletter.
Microbiologist-in-training who's also trying to keep up with the whole AI "situation." To me, it looks pretty serious.\ud83d\ude2c
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