Paired Ends
Stephen D. TurnerA practicing data scientist's take on AI, genomics, biosecurity, and the ways AI is reshaping how science gets done. Weekly updates from the field. Occasional notes on programming.
| Platform |  | Pricing | Only free issues | Publishes | Daily |
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blog.stephenturner.usLatest Issues
How to SNIFF out Good Scientific Software
For over a decade, the Ten Simple Rules and Quick Tips series at PLOS Computational Biology has told computational biologists how to build software the way software developers would.1 Hardly any of that guidance speaks to the researcher, th...
Turn new data into Quarto reports automatically
The watcher R package (watcher.r-lib.org) monitors your filesystem for changes, and can run code automatically when data is created or updated.
A helpful use case for this is to monitor a folder for changes, then render a Quarto report for...
Closing my tabs, July 10, 2026
GPT-5.6 came out yesterday. Plenty of other people are writing about it. I’m not yet, because I’m trying to be intentional about my AI use in July (it’s not going great — AI Dry July is more like an AI-damp-kinda-moist July). But, I was abl...
My Comment on OMB-2026-0034
I posted1 the following comment to OMB’s proposed rule changes to 2 CFR 200. If you’ve never heard of OMB or 2 CFR 200, I’ve included a few links at the end that explain what this is about and why this is bad for the American scientific ent...
Fewer Rungs on the Ladder
A few days into my AI Dry July, I finally read this new perspective paper arguing that AI will not replace bioinformaticians, but will move them up to higher value work: experimental design, interpretation, governance, deciding what to do n...
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