Pipeline to Patient
Suzanne VyvodaWriting about the operational realities behind modern drug development.
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 45 | Founded | a year ago | Last Issue | 10 days ago |
| Active | |||||
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concordiacompass.substack.comLatest Issues
Clinical Research Rewards a Different Kind of Optimism
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The most optimistic people I’ve worked with in clinical research are rarely the most cheerful.
They’re usually the ones asking the hardest questions.
The ones challenging enrollment assumptions.
The ones asking whether a t...
Prestige Doesn’t Enroll Patients
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Over the years, I’ve visited sites ranging from some of the most respected academic medical centers in the world to small community practices tucked into suburban office buildings.
Some had international reputations.
Some h...
How to Spot Clinical Trial Risk Before It Shows Up on a Dashboard
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Most people start by looking at the dashboard.
It’s understandable. Dashboards give us something tangible. Enrollment trends, site activations, protocol deviations, data quality metrics, issue logs—these are the indicators m...
Patients Don’t Fail Protocols. Protocols Fail Patients.
Something happened in your last trial.
Or it will happen in your next.
A patient reports perfect adherence.
Six weeks straight. Not a single missed dose.
But what if they’re not telling the full truth?
If you’ve worked in clinical tri...
The FDA Just Tested a Very Different Kind of Clinical Trial
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The FDA recently launched one of its first “real-time” clinical trial review pilots.
That may not sound remarkable until you realize most clinical trials are still reviewed more like historical reconstruction than live obser...
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Authors
The writers behind this newsletter.
Writing about the operational realities behind modern drug development.
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