Uncertainty Principles
Gary TaubesWhen what we don’t know is more important than what we do. Wrestling with conflict and controversy in science, medicine, health and nutrition.
| Platform |  | Pricing | Freemium | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 32 | Subscribers | Read | uncertaintyprinciples.substack.com |
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Chart Rankings
How this newsletter ranks in the official Substack charts.
| #175 | |
| #47 |
Latest Issues
Recent posts by this newsletter. Browse the email archive.
What's It Mean to Overeat? Lessons From a (Very) Fat Mouse & the Once "Not-Thin Peter" Attia.
Does the ob/ob mouse have anything in common with the influential longevity doctor, Peter Attia? If Dr. Attia's experience is any indication, the answer is a resounding yes.
Diet or Drugs for Diabetes? Which Comes First?
Question of the week: In an ideal world, who would you rather trust on the subject of diabetes care, the American Diabetes Association (ADA) with all its attendant expert committees and experts or an independent journalist with a Substack n...
Signs of Bad Science
> One critic of this body of research on BPA characterised it to me as, “a land of one-sided comparisons, confirmation bias, post-hoc reasoning, ‘any finding at any dose’ effects untethered from matters of precursor lesions, internal dosime...
Lessons From the Original (Very) Fat Mouse
Is it possible that obesity science went hopelessly off the rails 30 years ago because of one obese mouse and one researcher who didn’t do his homework? Short answer: yes.
Authors
The writers behind this newsletter.
Investigative science and health journalist, author of Rethinking Diabetes (2024), The Case for Keto (2020), The Case Against Sugar (2016), Why We Get Fat (2011), and Good Calories, Bad Calories (2007), published as The Diet Delusion in the UK.
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