
Integrative oncology clinician specializing in metabolic terrain and immune-based cancer care. Writing to replace fear with clarity and strategy.
| Platform | Pricing | Only free issues | Publishes | Weekly | |
|---|---|---|---|---|---|
| Issues | 51 | Founded | 9 months ago | Last Issue | 4 days ago |
| Active | |||||

I do not write very much about myself here. This an introspective piece. A journey that I have been on my whole life, but it is now just beginning.
Most of what I write is about cancer biology, treatment response, metabolism, immune funct...
“If the treatment worked, why is the tumor still there?”
It is such a reasonable question. We tend to think about cancer treatment in very physical terms: there was a tumor, treatment was given, and if the treatment worked, the tumor shoul...
Photo by Aika 愛和 on Unsplash
In The Cancer That Never Really Left, Part I of this discussion on metastatic dormancy, we challenged the familiar idea that cancer is treated, disappears, and then somehow “come...
Photo by Paulo Pescada on Unsplash
In the last article, The Seed, the Soil, and Why Cancer Spreads Where It Does, we looked at one of the most fascinating questions in metastasis: why certain cancers preferen...
Cancer metastasis has patterns. Prostate cancer has a striking affinity for bone. Colorectal and pancreatic cancers frequently metastasize to the liver. Uveal melanoma has an unusual and very strong preference for the liver. Soft-tissue sar...
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The writers behind this newsletter.
Janet Maendel DO(EUR) is an integrative oncology clinician whose work centers on immunometabolism & metabolic approaches to cancer care. She explores clinical reasoning, data interpretation, and the biological context beneath diagnosis.
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