Longevity Lifehacks
Join me in exploring the current research on healthspan and longevity. I'm focusing on practical solutions along with some out-of-the-box thinking as I try to turn back the biological clock.
| Platform |  | Pricing | Freemium | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 103 | Founded | 3 years ago | Last Issue | 8 days ago |
| Active | |||||
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longevitylifehacks.substack.comLatest Issues
From Irreversible to Repairable: Reversing AGEs
A new study published in the journal Nature Communications last week has me optimistic about reversing some of the detrimental effects of aging.
The study, titled “Reversal of protein chemical aging by enzymatic deglycation”, explains tha...
Brain energy changes in Alzheimer's connect to the benefits of low-dose lithium
New study showing glycolysis shift and neuroimmune changes prior to amyloid-β and tau tangles.
You may have heard Alzheimer’s described as type 3 diabetes, due to a shift in the way the brain uses glucose for energy. This description is of...
Aging at a cellular level
A new study in Nature Medicine (Ding et. al., 2026) lets us look inside to see how aging occurs differently across cell types — and how that contributes to the diseases of aging, such as cancer, neurodegenerative diseases, and frailty.
Co...
SIRT6 and Reversing DNA Changes in Aging
A new study in Nature Communications sheds light on a fundamental change in aging. The researchers showed that aging occurs in part due to DNA losing its organized structure inside cells. Importantly, they also showed that increasing a spec...
Topical Supplements for Preventing Skin Aging
Personal experiments using taurine or resveratrol topically.
Your skin is your biggest organ, and it is also like a big billboard declaring your age. When you go to the store, there seem to be a hundred options out there for antiaging skin...
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Authors
The writers behind this newsletter.
Exploring the science of healthspan and longevity by diving into the interesting studies and looking at how they can be applied. Debbie Moon is an author and founder of Genetic Lifehacks. www.GeneticLifehacks.com.
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