
Understanding neurodegeneration and aging through evidence, clarity, and practical insight. No hype, just facts.
| Platform | Pricing | Freemium | Publishes | Weekly | |
|---|---|---|---|---|---|
| Issues | 69 | Founded | a year ago | Last Issue | 4 days ago |
| Active | |||||

In this episode, we examine diranersen, also known as BIIB080, and the Phase 2 CELIA clinical trial. This experimental tau-targeting therapy reportedly reduced tau levels by 50–65% and was associated with slower cognitive decline on several...
Understanding Iron Deficiency and Anemia Beyond the Surface — Part 2
Erin Kovach stopped running three miles from her apartment, which was unusual for her.
A fast-moving outbreak of cyclosporiasis, an intestinal illness caused by the microscopic parasite Cyclospora cayetanensis, has become one of the largest on record in the U.S., and it is still growing. But if you have seen the numbers repor...
Diane is 48, and she has been tired for the better part of two years.
Not an ordinary kind of tiredness. It’s the kind sleep doesn’t touch. She takes the stairs at work and arrives at the top with her heart going like she’s been running. H...
I’ve spent the last stretch buried in the research on iron — reading the literature, following the threads, filling a whiteboard. It turns out to be a bigger, stranger, and more important subject than most people realize, and I wanted to un...
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| Subscribers | Engagement | 77 | Monthly Web Visits | ||
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The writers behind this newsletter.
Hi, I'm Harshi. I write early with coffee and a stack of research papers. I break down brain health from wherever I am, sometimes the lab and sometimes my kitchen table. Always clear, honest science that makes sense.
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