Harshi Peiris, Ph.D.
Understanding neurodegeneration and aging through evidence, clarity, and practical insight. No hype, just facts.
| Platform |  | Pricing | Freemium | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 74 | Founded | a year ago | Last Issue | 4 days ago |
| Active | |||||
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neuroscope.substack.comLatest Issues
The Brain's Missing Drain
What if part of Alzheimer’s isn’t just about the brain making too much toxic waste... but about the brain losing its ability to drain it?
That’s the theory behind a surgery now spreading across hospitals in China. Some patients with severe...
Beyond p-tau217: Rethinking Alzheimer's as a Spectrum of Subtypes
There’s a real excitement around p-tau217 right now, and I am too. Biomarkers and blood-based tests like this are a breakthrough for Alzheimer’s research because now we can detect risk of Alzheimer’s 10 years before disease symptoms hit.
B...
The Problem With Celebrating One Biomarker
Sporadic Alzheimer’s does not start the day a person’s symptoms appear. It starts 10-20 years before symptoms develop and gradually progresses. This timeline is called the prodromal period, where different risk factors work together to incr...
What if the fix for long COVID brain fog has been sitting in your pharmacy for decades, costing pennies a pill?
A landmark trial tracking 399 people crushed by chronic, post-viral exhaustion just dropped in the Annals of Internal Medicine. Researchers tested a cheap generic antidepressant, Fluvoxamine, against Metformin and a placebo.
Metformin fail...
Everything Has an Innocent Explanation
Marcus is 64 years old, and he has been feeling tired recently. He looked outside the window and told himself he was just getting older.
Marcus used to be an avid walker. He could run up the stairs to his apartment and still have ample ene...
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| Subscribers | Engagement | 77 | Monthly Web Visits | ||
|---|---|---|---|---|---|
| Accepts Sponsors | Estimated Cost per Ad | ||||
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Authors
The writers behind this newsletter.
Hi, I'm Harshi. I write early with coffee and a stack of research papers. I break down brain health from wherever I am, sometimes the lab and sometimes my kitchen table. Always clear, honest science that makes sense.
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